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Chil3 Gene Detail
Summary
  • Symbol
    Chil3
  • Name
    chitinase-like 3
  • Synonyms
    Chi3l3, Ym1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330860
    NCBI Gene: 12655
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr3:106054870-106074852 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.49 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    767 from dbSNP Build 142
  • Strain Annotations
    13
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330860
 protein coding gene Chr3:106054870-106074880 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027730
 protein coding gene Chr3:107545525-107648948 (-)
A/J MGP_AJ_G0027690
 protein coding gene Chr3:104112356-104210848 (-)
AKR/J MGP_AKRJ_G0027655
 protein coding gene Chr3:106704049-106793251 (-)
BALB/cJ MGP_BALBcJ_G0027702
 protein coding gene Chr3:103881875-103904005 (-)
C3H/HeJ MGP_C3HHeJ_G0027432
 protein coding gene Chr3:107038176-107141370 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028146
 protein coding gene Chr3:111588166-111663441 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0026888
 protein coding gene Chr3:106190367-106640601 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0027549
 protein coding gene Chr3:103349391-103415414 (-)
FVB/NJ MGP_FVBNJ_G0027517
 protein coding gene Chr3:101292376-101365413 (-)
LP/J MGP_LPJ_G0027656
 protein coding gene Chr3:108935769-108973448 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027547
 protein coding gene Chr3:121439286-121534836 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0026614
 protein coding gene Chr3:103138233-103143288 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CHIA, chitinase acidic
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHIA, chitinase acidic
  • Synonyms
    AMCASE, CHIT2, TSA1902
  • Links
    NCBI Gene ID: 27159
    neXtProt AC: NX_Q9BZP6
    UniProt: Q9BZP6

  • Chr Location
    1p13.2; chr1:111290851-111320566 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CHIA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    754
  • Tissues
    19
  • cDNA Data
    20
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12655 NCBI Gene Model | MGI Sequence Detail 19983 C57BL/6J ±  kb
transcript NM_009892 RefSeq | MGI Sequence Detail 1511 ZRU/MplStud  
polypeptide O35744 UniProt | EBI | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 20
    Primer pair 4

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139747
References
more
  • Summaries
    All 73
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 9
    Phenotypes 13
  • Earliest
    J:51389 Jin HM, et al., Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes. Genomics. 1998 Dec 1;54(2):316-22
  • Latest
    J:344843 Okawa K, et al., Irreversible evolutionary loss of chitin-degrading ability in the chitinase-like protein Ym1 under positive selection in rodents. Protein Sci. 2023 Apr;32(4):e4620
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory