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Srpk2 Gene Detail
Summary
  • Symbol
    Srpk2
  • Name
    serine/arginine-rich protein specific kinase 2
  • Synonyms
    mSRPK2, WBP6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201408
    NCBI Gene: 20817
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:23708262-23889615 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 10.36 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4355 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1201408
 protein coding gene Chr5:23708262-23889639 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029330
 protein coding gene Chr5:21160826-21350381 (-)
A/J MGP_AJ_G0029296
 protein coding gene Chr5:20477997-20653723 (-)
AKR/J MGP_AKRJ_G0029247
 protein coding gene Chr5:21274514-21468768 (-)
BALB/cJ MGP_BALBcJ_G0029307
 protein coding gene Chr5:20963518-21143719 (-)
C3H/HeJ MGP_C3HHeJ_G0029027
 protein coding gene Chr5:21362058-21554787 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029760
 protein coding gene Chr5:22637263-22826608 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026998
 protein coding gene Chr5:18431694-18611362 (-)
CAST/EiJ MGP_CASTEiJ_G0028439
 protein coding gene Chr5:20565605-20753627 (-)
CBA/J MGP_CBAJ_G0028994
 protein coding gene Chr5:22959039-23158529 (-)
DBA/2J MGP_DBA2J_G0029145
 protein coding gene Chr5:20739288-20915269 (-)
FVB/NJ MGP_FVBNJ_G0029103
 protein coding gene Chr5:20137342-20314673 (-)
LP/J MGP_LPJ_G0029229
 protein coding gene Chr5:21538274-21731251 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029132
 protein coding gene Chr5:24142336-24331830 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029794
 protein coding gene Chr5:20869121-21068064 (-)
PWK/PhJ MGP_PWKPhJ_G0028162
 protein coding gene Chr5:19822497-20005543 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027994
 protein coding gene Chr5:20272762-20456050 (-)
WSB/EiJ MGP_WSBEiJ_G0028519
 protein coding gene Chr5:20964716-21163281 (-)



Homology
more
  • Human Ortholog
    SRPK2, SRSF protein kinase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRPK2, SRSF protein kinase 2
  • Synonyms
    SFRSK2
  • Links
    NCBI Gene ID: 6733
    neXtProt AC: NX_P78362
    UniProt: P78362

  • Chr Location
    7q22.3; chr7:105110704-105399357 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from multigenic genotypes
    19 phenotype references
Mice homozygous for a targeted allele exhibit normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    70
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    786
  • Tissues
    21
  • cDNA Data
    33
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062604 Ensembl Gene Model | MGI Sequence Detail 181354 C57BL/6J ±  kb
transcript ENSMUST00000088392 Ensembl | MGI Sequence Detail 6491 Not Applicable  
polypeptide ENSMUSP00000085734 Ensembl | MGI Sequence Detail 682 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 37
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGD-MRK-39565, MGI:109566, MGI:2141179, MGI:2141199, MGI:2141220
References
more
  • Summaries
    All 59
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 10
    Phenotypes 19
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory