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C1qb Gene Detail
Summary
  • Symbol
    C1qb
  • Name
    complement component 1, q subcomponent, beta polypeptide
  • Feature Type
    protein coding gene
  • IDs
    MGI:88224
    NCBI Gene: 12260
  • Alliance
    gene page
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:136607440-136613498 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 69.05 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88224
 protein coding gene Chr4:136607437-136613511 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028973
 protein coding gene Chr4:139471871-139479180 (-)
A/J MGP_AJ_G0028932
 protein coding gene Chr4:133538319-133544476 (-)
AKR/J MGP_AKRJ_G0028884
 protein coding gene Chr4:137383736-137389810 (-)
BALB/cJ MGP_BALBcJ_G0028956
 protein coding gene Chr4:134198295-134208836 (-)
C3H/HeJ MGP_C3HHeJ_G0028670
 protein coding gene Chr4:137680182-137686102 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029397
 protein coding gene Chr4:144448989-144454906 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026668
 protein coding gene Chr4:126564918-126571141 (-)
CAST/EiJ MGP_CASTEiJ_G0028102
 protein coding gene Chr4:135828762-135835975 (-)
CBA/J MGP_CBAJ_G0028635
 protein coding gene Chr4:148440412-148449259 (-)
DBA/2J MGP_DBA2J_G0028784
 protein coding gene Chr4:133942044-133948012 (-)
FVB/NJ MGP_FVBNJ_G0028751
 protein coding gene Chr4:132902108-132908103 (-)
LP/J MGP_LPJ_G0028883
 protein coding gene Chr4:139558223-139565657 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028777
 protein coding gene Chr4:152579768-152586959 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029435
 protein coding gene Chr4:137863344-137870297 (-)
PWK/PhJ MGP_PWKPhJ_G0027822
 protein coding gene Chr4:130734530-130740572 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027648
 protein coding gene Chr4:133656218-133662167 (-)
WSB/EiJ MGP_WSBEiJ_G0028180
 protein coding gene Chr4:138022368-138028299 (-)



Homology
more
  • Human Ortholog
    C1QB, complement C1q B chain
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C1QB, complement C1q B chain
  • Synonyms
    C1QD2
  • Links
    NCBI Gene ID: 713
    neXtProt AC: NX_P02746
    UniProt: P02746

  • Chr Location
    1p36.12; chr1:22652762-22661637 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    4
  • Targeted
    5
  • Genomic Mutations
    3 involving C1qb
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    752
  • Tissues
    32
  • cDNA Data
    123
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036905 Ensembl Gene Model | MGI Sequence Detail 6059 C57BL/6J ±  kb
transcript ENSMUST00000046384 Ensembl | MGI Sequence Detail 1088 Not Applicable  
polypeptide ENSMUSP00000040246 Ensembl | MGI Sequence Detail 253 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 127
    Genomic 3
    cDNA 124

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-1697
References
more
  • Summaries
    All 58
    Developmental Gene Expression 6
    Gene Ontology 12
    Phenotypes 11
  • Earliest
    J:10130 Petry F, et al., Molecular cloning and characterization of the complementary DNA coding for the B-chain of murine Clq. FEBS Lett. 1989 Nov 20;258(1):89-93
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory