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Art2a Pseudogene Detail
Summary
  • Symbol
    Art2a
  • Name
    ADP-ribosyltransferase 2a
  • Synonyms
    Art2a-ps, Rt-6, Rt6, Rt6-1
Location &
Maps
more
  • Sequence Map
    Chr7:101201660-101210072 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.60 cM
  • Mapping Data
    13 experiments
Strain
Comparison
more
  • SNPs within 2kb
    306 from dbSNP Build 142
  • Strain Annotations
    4
  • RFLP
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107546
 polymorphic pseudogene Chr7:101201657-101210072 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0010168
 polymorphic pseudogene Chr7:108469133-108476973 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0009668
 polymorphic pseudogene Chr7:96238371-96271921 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0010138
 polymorphic pseudogene Chr7:103572148-103584545 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    22 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Art2a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    9 strains or lines available
A targeted mutation in this gene indirectly regulates T-cell apoptosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
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  • All Sequences
    20
  • RefSeq
    3
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000092517 Ensembl Gene Model | MGI Sequence Detail 8413 C57BL/6J ±  kb
transcript ENSMUST00000173420 Ensembl | MGI Sequence Detail 1257 Not Applicable  
polypeptide ENSMUSP00000134404 Ensembl | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Protein
Information
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Molecular
Reagents
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  • All nucleic 7
    Genomic 1
    cDNA 5
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-14246, MGD-MRK-14247, MGD-MRK-18653, MGD-MRK-36117, MGI:6280473
References
more
  • Summaries
    All 61
    Gene Ontology 6
    Phenotypes 22
  • Earliest
    J:10585 Koch F, et al., Nucleotide and deduced amino acid sequence for the mouse homologue of the rat T-cell differentiation marker RT6. Nucleic Acids Res. 1990 Jun 25;18(12):3636
  • Latest
    J:263067 Garcia-Rodriguez S, et al., CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism. Sci Rep. 2018 Feb 20;8(1):3357
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory