About   Help   FAQ
Htr5b Gene Detail
Summary
  • Symbol
    Htr5b
  • Name
    5-hydroxytryptamine (serotonin) receptor 5B
  • Feature Type
    protein coding gene
  • IDs
    MGI:96284
    NCBI Gene: 15564
  • Alliance
    gene page
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr1:121437571-121456194 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.98 cM, cytoband E4-G
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    620 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96284
 protein coding gene Chr1:121437487-121458351 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016411
 protein coding gene Chr1:124346588-124367272 (-)
A/J MGP_AJ_G0016394
 protein coding gene Chr1:119879701-119897531 (-)
AKR/J MGP_AKRJ_G0016359
 protein coding gene Chr1:123392905-123411856 (-)
BALB/cJ MGP_BALBcJ_G0016354
 protein coding gene Chr1:120160168-120178740 (-)
C3H/HeJ MGP_C3HHeJ_G0016180
 protein coding gene Chr1:123569528-123590771 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016815
 protein coding gene Chr1:129079391-129112034 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014528
 protein coding gene Chr1:113504711-113521238 (-)
CAST/EiJ MGP_CASTEiJ_G0015761
 protein coding gene Chr1:122392787-122411161 (-)
CBA/J MGP_CBAJ_G0016153
 protein coding gene Chr1:133540048-133566911 (-)
DBA/2J MGP_DBA2J_G0016259
 protein coding gene Chr1:118899884-118920465 (-)
FVB/NJ MGP_FVBNJ_G0016258
 protein coding gene Chr1:117665598-117683820 (-)
LP/J MGP_LPJ_G0016330
 protein coding gene Chr1:125694648-125714968 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016283
 protein coding gene Chr1:139227413-139248430 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016851
 protein coding gene Chr1:123153208-123175297 (-)
PWK/PhJ MGP_PWKPhJ_G0015547
 protein coding gene Chr1:117911842-117930103 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015335
 protein coding gene Chr1:122067085-122083894 (-)
WSB/EiJ MGP_WSBEiJ_G0015823
 protein coding gene Chr1:123029570-123053444 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    3 involving Htr5b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    20 strains or lines available
Mice homozygous for disruptions in this gene display a normal phenotype
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    72
  • cDNA Data
    6
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050534 Ensembl Gene Model | MGI Sequence Detail 18624 C57BL/6J ±  kb
transcript ENSMUST00000055884 Ensembl | MGI Sequence Detail 1935 Not Applicable  
polypeptide ENSMUSP00000057212 Ensembl | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 1
    cDNA 7
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11012
References
more
  • Summaries
    All 52
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 16
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:347117 Katada Y, et al., Starburst amacrine cells amplify optogenetic visual restoration through gap junctions. Mol Ther Methods Clin Dev. 2023 Sep 14;30:1-13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory