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Man1a Gene Detail
Summary
  • Symbol
    Man1a
  • Name
    mannosidase 1, alpha
  • Synonyms
    mannosyl-oligosaccharide alpha-1,2-mannosidase, PCR1
  • Feature Type
    protein coding gene
  • IDs
    MGI:104677
    NCBI Gene: 17155
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:53780881-53952705 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 27.40 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5026 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104677
 protein coding gene Chr10:53780881-53952712 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017233
 protein coding gene Chr10:53096722-53280434 (-)
A/J MGP_AJ_G0017209
 protein coding gene Chr10:51527666-51702331 (-)
AKR/J MGP_AKRJ_G0017169
 protein coding gene Chr10:52537255-52715950 (-)
BALB/cJ MGP_BALBcJ_G0017170
 protein coding gene Chr10:51665261-51835900 (-)
C3H/HeJ MGP_C3HHeJ_G0016993
 protein coding gene Chr10:52802000-52981737 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017629
 protein coding gene Chr10:54764283-54948782 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015323
 protein coding gene Chr10:48687423-48859842 (-)
CAST/EiJ MGP_CASTEiJ_G0016566
 protein coding gene Chr10:52892053-53073044 (-)
CBA/J MGP_CBAJ_G0016965
 protein coding gene Chr10:57060799-57250124 (-)
DBA/2J MGP_DBA2J_G0017070
 protein coding gene Chr10:50965491-51139340 (-)
FVB/NJ MGP_FVBNJ_G0017065
 protein coding gene Chr10:50262061-50434119 (-)
LP/J MGP_LPJ_G0017145
 protein coding gene Chr10:53166399-53351790 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017094
 protein coding gene Chr10:59033285-59225932 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017666
 protein coding gene Chr10:52464358-52643650 (-)
PWK/PhJ MGP_PWKPhJ_G0016347
 protein coding gene Chr10:50810312-50986802 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016133
 protein coding gene Chr10:52090473-52278456 (-)
WSB/EiJ MGP_WSBEiJ_G0016631
 protein coding gene Chr10:52703965-52883482 (-)



Homology
more
  • Human Ortholog
    MAN1A1, mannosidase alpha class 1A member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAN1A1, mannosidase alpha class 1A member 1
  • Synonyms
    HUMM3, HUMM9, MAN9
  • Links
    NCBI Gene ID: 4121
    neXtProt AC: NX_P33908
    UniProt: P33908

  • Chr Location
    6q22.31; chr6:119177205-119350605 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    966
  • Tissues
    162
  • cDNA Data
    103
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003746 Ensembl Gene Model | MGI Sequence Detail 171825 C57BL/6J ±  kb
transcript ENSMUST00000220088 Ensembl | MGI Sequence Detail 2354 Not Applicable  
polypeptide ENSMUSP00000151568 Ensembl | MGI Sequence Detail 744 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 109
    cDNA 104
    Primer pair 5

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-27040
References
more
  • Summaries
    All 45
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:296696 Zhang L, et al., Satb2 is required for the regionalization of retrosplenial cortex. Cell Death Differ. 2020 May;27(5):1604-1617
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory