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Cox8b Gene Detail
Summary
  • Symbol
    Cox8b
  • Name
    cytochrome c oxidase subunit 8B
  • Synonyms
    COX8H, COX VIII-H
  • Feature Type
    protein coding gene
  • IDs
    MGI:105958
    NCBI Gene: 12869
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140478858-140480359 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.11 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105958
 protein coding gene Chr7:140478855-140480359 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033199
 protein coding gene Chr7:146036168-146037671 (-)
A/J MGP_AJ_G0033181
 protein coding gene Chr7:141882844-141884347 (-)
AKR/J MGP_AKRJ_G0033113
 protein coding gene Chr7:145773577-145775080 (-)
BALB/cJ MGP_BALBcJ_G0033182
 protein coding gene Chr7:141610709-141612212 (-)
C3H/HeJ MGP_C3HHeJ_G0032896
 protein coding gene Chr7:145530542-145532045 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033693
 protein coding gene Chr7:151381944-151383447 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030666
 protein coding gene Chr7:143091275-143092759 (-)
CAST/EiJ MGP_CASTEiJ_G0032226
 protein coding gene Chr7:137828294-137829797 (-)
CBA/J MGP_CBAJ_G0032868
 protein coding gene Chr7:156508746-156510249 (-)
DBA/2J MGP_DBA2J_G0033021
 protein coding gene Chr7:139820303-139821806 (-)
FVB/NJ MGP_FVBNJ_G0032973
 protein coding gene Chr7:139733332-139734835 (-)
LP/J MGP_LPJ_G0033115
 protein coding gene Chr7:147538125-147539628 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033006
 protein coding gene Chr7:157172968-157174471 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033713
 protein coding gene Chr7:144757737-144759240 (-)
PWK/PhJ MGP_PWKPhJ_G0031931
 protein coding gene Chr7:133092372-133093875 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031777
 protein coding gene Chr7:131573814-131575252 (-)
WSB/EiJ MGP_WSBEiJ_G0032337
 protein coding gene Chr7:145677812-145679315 (-)



Homology
more
  • Human Ortholog
    COX8BP, cytochrome c oxidase subunit 8B, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX8BP, cytochrome c oxidase subunit 8B, pseudogene
  • Synonyms
    COX8-1, COX8B, COX8H
  • Links
    NCBI Gene ID: 404544

  • Chr Location
    11p15.5; chr11:253417-256972 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    14
  • Endonuclease-mediated
    1
  • Gene trapped
    10
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Cox8b
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    831
  • Tissues
    104
  • cDNA Data
    22
  • Literature Summary
    19
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025488 Ensembl Gene Model | MGI Sequence Detail 1502 C57BL/6J ±  kb
transcript ENSMUST00000026561 Ensembl | MGI Sequence Detail 360 Not Applicable  
polypeptide ENSMUSP00000026561 Ensembl | MGI Sequence Detail 70 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    Genomic 1
    cDNA 22
    Primer pair 5
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33637
References
more
  • Summaries
    All 54
    Developmental Gene Expression 19
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:24248 Hegeman AD, et al., Sequence of the cDNA for the heart/muscle isoform of mouse cytochrome c oxidase subunit VIII. Biochim Biophys Acta. 1995 Apr 4;1261(2):311-4
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory