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Csrnp1 Gene Detail
Summary
  • Symbol
    Csrnp1
  • Name
    cysteine-serine-rich nuclear protein 1
  • Synonyms
    4931429D10Rik, Axud1, CSRNP-1, taip-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387989
    NCBI Gene: 215418
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:119800229-119813724 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 71.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    335 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387989
 protein coding gene Chr9:119800229-119813808 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035428
 protein coding gene Chr9:122782146-122795705 (-)
A/J MGP_AJ_G0035409
 protein coding gene Chr9:118183931-118197237 (-)
AKR/J MGP_AKRJ_G0035341
 protein coding gene Chr9:121278196-121290663 (-)
BALB/cJ MGP_BALBcJ_G0035404
 protein coding gene Chr9:118072639-118085701 (-)
C3H/HeJ MGP_C3HHeJ_G0035112
 protein coding gene Chr9:121749569-121761732 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035927
 protein coding gene Chr9:126145128-126159181 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032810
 protein coding gene Chr9:115392153-115404709 (-)
CAST/EiJ MGP_CASTEiJ_G0034417
 protein coding gene Chr9:121758414-121773677 (-)
CBA/J MGP_CBAJ_G0035079
 protein coding gene Chr9:130851274-130865978 (-)
DBA/2J MGP_DBA2J_G0035238
 protein coding gene Chr9:117635560-117648158 (-)
FVB/NJ MGP_FVBNJ_G0035185
 protein coding gene Chr9:116514516-116526808 (-)
LP/J MGP_LPJ_G0035317
 protein coding gene Chr9:123116046-123128268 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035227
 protein coding gene Chr9:131788097-131804149 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035947
 protein coding gene Chr9:121668516-121682180 (-)
PWK/PhJ MGP_PWKPhJ_G0034122
 protein coding gene Chr9:118076937-118089572 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033958
 protein coding gene Chr9:121767192-121779700 (-)
WSB/EiJ MGP_WSBEiJ_G0034537
 protein coding gene Chr9:121555191-121567455 (-)



Homology
more
  • Human Ortholog
    CSRNP1, cysteine and serine rich nuclear protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSRNP1, cysteine and serine rich nuclear protein 1
  • Synonyms
    AXUD1, CSRNP-1, FAM130B, TAIP-3, URAX1
  • Links
    NCBI Gene ID: 64651
    neXtProt AC: NX_Q96S65
    UniProt: Q96S65

  • Chr Location
    3p22.2; chr3:39141855-39154641 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit postnatal lethality and skeletal and craniofacial defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    10
  • cDNA Data
    10
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032515 Ensembl Gene Model | MGI Sequence Detail 13496 C57BL/6J ±  kb
    transcript ENSMUST00000035101 Ensembl | MGI Sequence Detail 2906 Not Applicable  
    polypeptide ENSMUSP00000035101 Ensembl | MGI Sequence Detail 583 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000004529 Axin-1 up-regulated gene 1 protein
      (term hierarchy)
    • InterPro Domains
      IPR023260 Cysteine/serine-rich nuclear protein family
      IPR031972 Cysteine/serine-rich nuclear protein, N-terminal domain
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2444212
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:261308 Ye X, et al., Axin1 up-regulated 1 accelerates stress-induced cardiomyocytes apoptosis through activating Wnt/beta-catenin signaling. Exp Cell Res. 2017 Oct 15;359(2):441-448
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    10/29/2024
    MGI 6.24     		The Jackson Laboratory