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Rab2b Gene Detail
Summary
  • Symbol
    Rab2b
  • Name
    RAB2B, member RAS oncogene family
  • Synonyms
    1500012D09Rik, 4930528G15Rik, D530043M21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923588
    NCBI Gene: 76338
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:52499216-52516852 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 26.87 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    528 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923588
 protein coding gene Chr14:52499216-52517002 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021294
 protein coding gene Chr14:46296011-46314120 (-)
A/J MGP_AJ_G0021251
 protein coding gene Chr14:45079087-45097205 (-)
AKR/J MGP_AKRJ_G0021227
 protein coding gene Chr14:46704886-46728527 (-)
BALB/cJ MGP_BALBcJ_G0021255
 protein coding gene Chr14:45186857-45204151 (-)
C3H/HeJ MGP_C3HHeJ_G0021035
 protein coding gene Chr14:46516132-46534998 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021694
 protein coding gene Chr14:48355743-48373403 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019238
 protein coding gene Chr14:44282828-44302579 (-)
CAST/EiJ MGP_CASTEiJ_G0020554
 protein coding gene Chr14:43490185-43507693 (-)
CBA/J MGP_CBAJ_G0021002
 protein coding gene Chr14:49802221-49823431 (-)
DBA/2J MGP_DBA2J_G0021123
 protein coding gene Chr14:44853831-44871739 (-)
FVB/NJ MGP_FVBNJ_G0021106
 protein coding gene Chr14:44434818-44453165 (-)
LP/J MGP_LPJ_G0021198
 protein coding gene Chr14:46891277-46908347 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021129
 protein coding gene Chr14:49252753-49272473 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021721
 protein coding gene Chr14:46092238-46110080 (-)
PWK/PhJ MGP_PWKPhJ_G0020303
 protein coding gene Chr14:41594105-41613314 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020130
 protein coding gene Chr14:42133180-42150819 (-)
WSB/EiJ MGP_WSBEiJ_G0020607
 protein coding gene Chr14:46421088-46441094 (-)



Homology
more
  • Human Ortholog
    RAB2B, RAB2B, member RAS oncogene family
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB2B, RAB2B, member RAS oncogene family
  • Links
    NCBI Gene ID: 84932
    neXtProt AC: NX_Q8WUD1
    UniProt: Q8WUD1

  • Chr Location
    14q11.2; chr14:21459020-21476960 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Targeted
    2
  • Genomic Mutations
    1 involving Rab2b
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    822
  • Tissues
    11
  • cDNA Data
    36
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76338 NCBI Gene Model | MGI Sequence Detail 17637 C57BL/6J ±  kb
transcript NM_172601 RefSeq | MGI Sequence Detail 2770 C57BL/6  
polypeptide P59279 UniProt | EBI | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 7
Other
Accession IDs
less
MGI:1922051, MGI:1926108
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 11
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:314135 Morohoshi A, et al., FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice. Development. 2021 Nov 1;148(21):dev199644
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory