Rps15 MGI Mouse Gene Detail - MGI:98117

Symbol

Rps15
Name

ribosomal protein S15
Synonyms

insulinoma, rat insulinoma gene, rig

Feature Type

protein coding gene
IDs

MGI:98117
NCBI Gene: 20054
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr10:80128287-80129948 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 39.72 cM, cytoband C1
Mapping Data

1 experiment

SNPs within 2kb

132 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_98117	protein coding gene	Chr10:80128265-80129948 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017493	protein coding gene	Chr10:80892104-80893739 (+)
A/J	MGP_AJ_G0017471	protein coding gene	Chr10:78057919-78059554 (+)
AKR/J	MGP_AKRJ_G0017432	protein coding gene	Chr10:80194901-80196536 (+)
BALB/cJ	MGP_BALBcJ_G0017433	protein coding gene	Chr10:78288460-78290095 (+)
C3H/HeJ	MGP_C3HHeJ_G0017256	protein coding gene	Chr10:80287220-80288856 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017887	protein coding gene	Chr10:83694029-83696222 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015575	protein coding gene	Chr10:74279651-74281249 (+)
CAST/EiJ	MGP_CASTEiJ_G0016823	protein coding gene	Chr10:80490938-80497570 (+)
CBA/J	MGP_CBAJ_G0017228	protein coding gene	Chr10:86922066-86925481 (+)
DBA/2J	MGP_DBA2J_G0017334	protein coding gene	Chr10:77277234-77278866 (+)
FVB/NJ	MGP_FVBNJ_G0017328	protein coding gene	Chr10:76465284-76467242 (+)
LP/J	MGP_LPJ_G0017405	protein coding gene	Chr10:81363862-81365523 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017354	protein coding gene	Chr10:88867019-88868654 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017928	protein coding gene	Chr10:80182586-80184221 (+)
PWK/PhJ	MGP_PWKPhJ_G0016604	protein coding gene	Chr10:77145976-77147757 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016393	protein coding gene	Chr10:79154583-79157065 (+)
WSB/EiJ	MGP_WSBEiJ_G0016883	protein coding gene	Chr10:80215401-80217037 (+)

Human Ortholog

RPS15, ribosomal protein S15

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPS15, ribosomal protein S15
Synonyms

RIG, S15, uS19
Links

HGNC:10388

NCBI Gene ID: 6209

neXtProt AC: NX_P62841

UniProt: P62841
Chr Location

19p13.3; chr19:1438358-1440495 (+) GRCh38

MGI Vertebrate Homology

Rps15 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPS15
Protein SuperFamily

Ribosomal_S19
Gene Tree

Rps15

less

Phenotype Summary

11 phenotype references

All Mutations and Alleles

33
Chemically induced (other)

1
Gene trapped

31
Targeted

1
Genomic Mutations

1 involving Rps15
Incidental Mutations

APF
Find Mice (IMSR)

17 strains or lines available

less

All GO Annotations

30
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

593
Literature Summary

5

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rps15

less

All Sequences

44
RefSeq

4
UniProt

4
CCDS

CCDS35978.1, CCDS78858.1

Ensembl

ENSMUSG00000063457 (Evidence)
NCBI Gene

20054

			Length	Strain/Species	Flank
genomic	ENSMUSG00000063457	Ensembl Gene Model \| MGI Sequence Detail	1662	C57BL/6J	± kb
transcript	ENSMUST00000068408	Ensembl \| MGI Sequence Detail	500	Not Applicable
polypeptide	ENSMUSP00000069004	Ensembl \| MGI Sequence Detail	145	Not Applicable

less

UniProt

4 Sequences
Protein Ontology

PR:000014256 eukaryotic-type small ribosomal subunit protein uS19

(term hierarchy)
PDB

7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR002222 Small ribosomal subunit protein uS19

IPR020934 Small ribosomal subunit protein uS19, conserved site

IPR005713 Small ribosomal subunit protein uS19, eukaryotic/archaeal

IPR023575 Small ribosomal subunit protein uS19, superfamily
GlyGen

P62843 1 site, 1 O-linked glycan (1 site)

less

All nucleic 594

cDNA 594

Microarray probesets 6

less

MGD-MRK-14143

Summaries

All 45

Developmental Gene Expression 5

Gene Ontology 8

Phenotypes 11
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rps15:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr94541	Chr10:80128248-80128270 (+)	-28 bp
Tssr94542	Chr10:80128287-80128329 (+)	21 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24