Rpl19 MGI Mouse Gene Detail - MGI:98020

Symbol

Rpl19
Name

ribosomal protein L19

Feature Type

protein coding gene
IDs

MGI:98020
NCBI Gene: 19921
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr11:97917536-97921318 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 61.56 cM, cytoband D
Mapping Data

2 experiments

SNPs within 2kb

202 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_98020	protein coding gene	Chr11:97912829-97921319 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019048	protein coding gene	Chr11:100520461-100523992 (+)
A/J	MGP_AJ_G0019016	protein coding gene	Chr11:96359648-96363173 (+)
AKR/J	MGP_AKRJ_G0018986	protein coding gene	Chr11:99348068-99354198 (+)
BALB/cJ	MGP_BALBcJ_G0018989	protein coding gene	Chr11:96858543-96862068 (+)
C3H/HeJ	MGP_C3HHeJ_G0018803	protein coding gene	Chr11:99478764-99483420 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019442	protein coding gene	Chr11:103612352-103619684 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017073	protein coding gene	Chr11:93812927-93816407 (+)
CAST/EiJ	MGP_CASTEiJ_G0018357	protein coding gene	Chr11:100344696-100348213 (+)
CBA/J	MGP_CBAJ_G0018774	protein coding gene	Chr11:107902362-107909004 (+)
DBA/2J	MGP_DBA2J_G0018882	protein coding gene	Chr11:95910041-95913572 (+)
FVB/NJ	MGP_FVBNJ_G0018871	protein coding gene	Chr11:95408645-95416204 (+)
LP/J	MGP_LPJ_G0018952	protein coding gene	Chr11:101009583-101015176 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018898	protein coding gene	Chr11:107722425-107727397 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019482	protein coding gene	Chr11:99668142-99672847 (+)
PWK/PhJ	MGP_PWKPhJ_G0018129	protein coding gene	Chr11:96896589-96904827 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017919	protein coding gene	Chr11:99383235-99389349 (+)
WSB/EiJ	MGP_WSBEiJ_G0018407	protein coding gene	Chr11:99571183-99578539 (+)

Human Ortholog

RPL19, ribosomal protein L19

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL19, ribosomal protein L19
Synonyms

eL19, L19
Links

HGNC:10312

NCBI Gene ID: 6143

neXtProt AC: NX_P84098

UniProt: P84098
Chr Location

17q12; chr17:39200283-39204840 (+) GRCh38

MGI Vertebrate Homology

Rpl19 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPL19
Gene Tree

Rpl19

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

28
Gene trapped

27
Targeted

1
Genomic Mutations

1 involving Rpl19
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

6 strains or lines available

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All GO Annotations

22
GO References

10

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

715
Tissues

8
cDNA Data

357
Literature Summary

6

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl19

ZFIN rpl19

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All Sequences

57
RefSeq

12
UniProt

3
CCDS

CCDS25337.1, CCDS48900.1

Ensembl

ENSMUSG00000017404 (Evidence)
NCBI Gene

19921

			Length	Strain/Species	Flank
genomic	ENSMUSG00000017404	Ensembl Gene Model \| MGI Sequence Detail	3783	C57BL/6J	± kb
transcript	ENSMUST00000017548	Ensembl \| MGI Sequence Detail	751	Not Applicable
polypeptide	ENSMUSP00000017548	Ensembl \| MGI Sequence Detail	196	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000014199 large ribosomal subunit protein eL19

(term hierarchy)
PDB

1K8D, 6SWA, 7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR039547 Large ribosomal subunit protein eL19

IPR023638 Large ribosomal subunit protein eL19, conserved site

IPR000196 Large ribosomal subunit protein eL19 domain

IPR015972 Large ribosomal subunit protein eL19, domain 1

IPR033935 Large ribosomal subunit protein eL19, eukaryotic

IPR035970 Large ribosomal subunit protein eL19 superfamily
GlyGen

P84099 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)

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All nucleic 358

cDNA 357

Primer pair 1

Microarray probesets 9

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MGD-MRK-14043

Summaries

All 48

Developmental Gene Expression 6

Gene Ontology 10

Phenotypes 8
Earliest

J:31514 Meyuhas O, et al., Construction and identification of cDNA clones for mouse ribosomal proteins: application for the study of r-protein gene expression. Gene. 1980 Jul;10(2):113-29
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rpl19:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr104698	Chr11:97917521-97917570 (+)	10 bp
Tssr104699	Chr11:97917744-97917757 (+)	215 bp
Tssr104700	Chr11:97917765-97917794 (+)	244 bp
Tssr104701	Chr11:97917809-97917818 (+)	278 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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