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Ano9 Gene Detail
Summary
  • Symbol
    Ano9
  • Name
    anoctamin 9
  • Synonyms
    5430425C04Rik, Tmem16j, Tp53i5, Trp53i5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918595
    NCBI Gene: 71345
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140681125-140697719 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    429 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918595
 protein coding gene Chr7:140681125-140697719 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033211
 protein coding gene Chr7:146270927-146289240 (-)
A/J MGP_AJ_G0033193
 protein coding gene Chr7:142089717-142106688 (-)
AKR/J MGP_AKRJ_G0033125
 protein coding gene Chr7:146005790-146022866 (-)
BALB/cJ MGP_BALBcJ_G0033194
 protein coding gene Chr7:141831022-141848179 (-)
C3H/HeJ MGP_C3HHeJ_G0032908
 protein coding gene Chr7:145756185-145773545 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033705
 protein coding gene Chr7:151621032-151640141 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030678
 protein coding gene Chr7:143301106-143318402 (-)
CAST/EiJ MGP_CASTEiJ_G0032238
 protein coding gene Chr7:138059961-138083110 (-)
CBA/J MGP_CBAJ_G0032880
 protein coding gene Chr7:156729750-156746319 (-)
DBA/2J MGP_DBA2J_G0033032
 protein coding gene Chr7:140039554-140056175 (-)
FVB/NJ MGP_FVBNJ_G0032985
 protein coding gene Chr7:139941984-139958624 (-)
LP/J MGP_LPJ_G0033127
 protein coding gene Chr7:147756683-147773272 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033018
 protein coding gene Chr7:157414715-157432511 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033725
 protein coding gene Chr7:144985485-145002072 (-)
PWK/PhJ MGP_PWKPhJ_G0031942
 protein coding gene Chr7:133315820-133333353 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031789
 protein coding gene Chr7:131797382-131816048 (-)
WSB/EiJ MGP_WSBEiJ_G0032349
 protein coding gene Chr7:145932179-145948854 (-)



Homology
more
  • Human Ortholog
    ANO9, anoctamin 9
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANO9, anoctamin 9
  • Synonyms
    PIG5, TMEM16J, TP53I5
  • Links
    NCBI Gene ID: 338440
    neXtProt AC: NX_A1A5B4
    UniProt: A1A5B4

  • Chr Location
    11p15.5; chr11:417933-442011 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    13
  • cDNA Data
    24
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71345 NCBI Gene Model | MGI Sequence Detail 16595 C57BL/6J ±  kb
transcript NM_178381 RefSeq | MGI Sequence Detail 3012 C57BL/6  
polypeptide P86044 UniProt | EBI | MGI Sequence Detail 747 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 9
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:352392 Schreiber R, et al., A TMEM16J variant leads to dysregulated cytosolic calcium which may lead to renal disease. FASEB J. 2023 Jan;37(1):e22683
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory