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Nrsn1 Gene Detail
Summary
  • Symbol
    Nrsn1
  • Name
    neurensin 1
  • Synonyms
    Neurensin-1, Neuro-p24, Vmp
  • Feature Type
    protein coding gene
  • IDs
    MGI:894662
    NCBI Gene: 22360
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:25436022-25453979 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 11.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    623 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894662
 protein coding gene Chr13:25436022-25454485 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020388
 protein coding gene Chr13:22760738-22781638 (-)
A/J MGP_AJ_G0020337
 protein coding gene Chr13:22335726-22354188 (-)
AKR/J MGP_AKRJ_G0020317
 protein coding gene Chr13:22580983-22599450 (-)
BALB/cJ MGP_BALBcJ_G0020335
 protein coding gene Chr13:22315983-22334445 (-)
C3H/HeJ MGP_C3HHeJ_G0020139
 protein coding gene Chr13:22647655-22666117 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020772
 protein coding gene Chr13:23547970-23566432 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018360
 protein coding gene Chr13:21031354-21050012 (-)
CAST/EiJ MGP_CASTEiJ_G0019656
 protein coding gene Chr13:22367303-22385897 (-)
CBA/J MGP_CBAJ_G0020093
 protein coding gene Chr13:24463962-24482424 (-)
DBA/2J MGP_DBA2J_G0020219
 protein coding gene Chr13:21824887-21843349 (-)
FVB/NJ MGP_FVBNJ_G0020203
 protein coding gene Chr13:21477558-21496020 (-)
LP/J MGP_LPJ_G0020292
 protein coding gene Chr13:23060875-23079337 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020230
 protein coding gene Chr13:24683778-24703570 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020814
 protein coding gene Chr13:22437095-22455557 (-)
PWK/PhJ MGP_PWKPhJ_G0019410
 protein coding gene Chr13:21832244-21851215 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019226
 protein coding gene Chr13:21269709-21290929 (-)
WSB/EiJ MGP_WSBEiJ_G0019716
 protein coding gene Chr13:22596301-22615793 (-)



Homology
more
  • Human Ortholog
    NRSN1, neurensin 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NRSN1, neurensin 1
  • Synonyms
    p24, VMP
  • Links
    NCBI Gene ID: 140767
    neXtProt AC: NX_Q8IZ57
    UniProt: Q8IZ57

  • Chr Location
    6p22.3; chr6:24126186-24154900 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    906
  • Tissues
    54
  • cDNA Data
    22
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22360 NCBI Gene Model | MGI Sequence Detail 17958 C57BL/6J ±  kb
transcript NM_001426601 RefSeq | MGI Sequence Detail 2258 C57BL/6  
polypeptide P97799 UniProt | EBI | MGI Sequence Detail 196 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory