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Atp5me Gene Detail
Summary
  • Symbol
    Atp5me
  • Name
    ATP synthase membrane subunit e
  • Synonyms
    2610008D24Rik, Atp5k, Lfm1
  • Feature Type
    protein coding gene
  • IDs
    MGI:106636
    NCBI Gene: 11958
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:108581112-108582265 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.11 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    2
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106636
 protein coding gene Chr5:108581110-108582314 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029855
 protein coding gene Chr5:110546588-110547792 (-)
A/J MGP_AJ_G0029819
 protein coding gene Chr5:106296780-106297984 (-)
AKR/J MGP_AKRJ_G0029764
 protein coding gene Chr5:109722316-109723520 (-)
BALB/cJ MGP_BALBcJ_G0029831
 protein coding gene Chr5:107437634-107438838 (-)
C3H/HeJ MGP_C3HHeJ_G0029553
 protein coding gene Chr5:110216791-110217994 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030285
 protein coding gene Chr5:115046460-115047664 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027519
 protein coding gene Chr5:101315663-101316877 (-)
CAST/EiJ MGP_CASTEiJ_G0028967
 protein coding gene Chr5:109108179-109109381 (-)
CBA/J MGP_CBAJ_G0029521
 protein coding gene Chr5:118956850-118958053 (-)
DBA/2J MGP_DBA2J_G0029667
 protein coding gene Chr5:106427863-106429067 (-)
FVB/NJ MGP_FVBNJ_G0029624
 protein coding gene Chr5:105155422-105156625 (-)
LP/J MGP_LPJ_G0029755
 protein coding gene Chr5:111126965-111128169 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029656
 protein coding gene Chr5:123851174-123852378 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030319
 protein coding gene Chr5:109285148-109286352 (-)
PWK/PhJ MGP_PWKPhJ_G0028680
 protein coding gene Chr5:105248592-105250043 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028518
 protein coding gene Chr5:106800038-106801231 (-)
WSB/EiJ MGP_WSBEiJ_G0029040
 protein coding gene Chr5:109595487-109596691 (-)



Homology
more
  • Human Ortholog
    ATP5ME, ATP synthase membrane subunit e
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5ME, ATP synthase membrane subunit e
  • Synonyms
    ATP5I, ATP5K
  • Links
    NCBI Gene ID: 521
    neXtProt AC: NX_P56385
    UniProt: P56385

  • Chr Location
    4p16.3; chr4:672436-674330 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    33
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    26
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Atp5me
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    823
  • Tissues
    97
  • cDNA Data
    169
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 11958 NCBI Gene Model | MGI Sequence Detail 1154 C57BL/6J ±  kb
transcript NM_007507 RefSeq | MGI Sequence Detail 338 ZRU/MplStud  
polypeptide Q06185 UniProt | EBI | MGI Sequence Detail 71 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004460 ATP synthase subunit e, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR008386 ATP synthase, F0 complex, subunit E, mitochondrial
  • GlyGen
    Q06185 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 174
    Genomic 3
    cDNA 169
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11788, MGD-MRK-35093, MGI:1917284, MGI:7469645
References
more
  • Summaries
    All 49
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:346630 Zhang X, et al., Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory