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Lvrn Gene Detail
Summary
  • Symbol
    Lvrn
  • Name
    laeverin
  • Synonyms
    4833403I15Rik, Aqpep
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921824
    NCBI Gene: 74574
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46983105-47040309 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 24.84 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1663 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921824
 protein coding gene Chr18:46983105-47040313 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024414
 protein coding gene Chr18:45682360-45770731 (+)
A/J MGP_AJ_G0024381
 protein coding gene Chr18:44027408-44082449 (+)
AKR/J MGP_AKRJ_G0024350
 protein coding gene Chr18:45234903-45290551 (+)
BALB/cJ MGP_BALBcJ_G0024381
 protein coding gene Chr18:44131880-44188803 (+)
C3H/HeJ MGP_C3HHeJ_G0024148
 protein coding gene Chr18:45328349-45382751 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024825
 protein coding gene Chr18:47288881-47352917 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022260
 protein coding gene Chr18:43834041-43889736 (+)
CAST/EiJ MGP_CASTEiJ_G0023622
 protein coding gene Chr18:45264527-45353912 (+)
CBA/J MGP_CBAJ_G0024117
 protein coding gene Chr18:48570546-48629795 (+)
DBA/2J MGP_DBA2J_G0024247
 protein coding gene Chr18:43633806-43690079 (+)
FVB/NJ MGP_FVBNJ_G0024213
 protein coding gene Chr18:43202084-43256159 (+)
LP/J MGP_LPJ_G0024331
 protein coding gene Chr18:45741313-45834316 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024244
 protein coding gene Chr18:49937209-50002385 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024872
 protein coding gene Chr18:45156689-45247833 (+)
PWK/PhJ MGP_PWKPhJ_G0023365
 protein coding gene Chr18:43778807-43865072 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023171
 protein coding gene Chr18:45302737-45378919 (+)
WSB/EiJ MGP_WSBEiJ_G0023685
 protein coding gene Chr18:45050479-45107386 (+)



Homology
more
  • Human Ortholog
    LVRN, laeverin
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LVRN, laeverin
  • Synonyms
    APQ, AQPEP, TAQPEP
  • Links
    NCBI Gene ID: 206338
    neXtProt AC: NX_Q6Q4G3
    UniProt: Q6Q4G3

  • Chr Location
    5q23.1; chr5:115962454-116027619 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Homozygous inactivation of this gene results in normal placentation and fetal development with no alterations in maternal blood pressure during pregnancy.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    16
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024481 Ensembl Gene Model | MGI Sequence Detail 57205 C57BL/6J ±  kb
transcript ENSMUST00000025358 Ensembl | MGI Sequence Detail 5016 Not Applicable  
polypeptide ENSMUSP00000025358 Ensembl | MGI Sequence Detail 991 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory