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Hexim2 Gene Detail
Summary
  • Symbol
    Hexim2
  • Name
    hexamethylene bis-acetamide inducible 2
  • Synonyms
    4933402L21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918309
    NCBI Gene: 71059
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:103023255-103030702 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 66.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    225 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918309
 protein coding gene Chr11:103014086-103030734 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019257
 protein coding gene Chr11:106176411-106185916 (+)
A/J MGP_AJ_G0019225
 protein coding gene Chr11:101674026-101681280 (+)
AKR/J MGP_AKRJ_G0019194
 protein coding gene Chr11:104810672-104818093 (+)
BALB/cJ MGP_BALBcJ_G0019199
 protein coding gene Chr11:102146146-102153901 (+)
C3H/HeJ MGP_C3HHeJ_G0019008
 protein coding gene Chr11:105034917-105044235 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019648
 protein coding gene Chr11:109485025-109496222 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017274
 protein coding gene Chr11:99091220-99098430 (+)
CAST/EiJ MGP_CASTEiJ_G0018562
 protein coding gene Chr11:106050287-106059276 (+)
CBA/J MGP_CBAJ_G0018977
 protein coding gene Chr11:114034513-114044711 (+)
DBA/2J MGP_DBA2J_G0019089
 protein coding gene Chr11:101186720-101194386 (+)
FVB/NJ MGP_FVBNJ_G0019079
 protein coding gene Chr11:100728390-100735805 (+)
LP/J MGP_LPJ_G0019158
 protein coding gene Chr11:106695250-106704513 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019110
 protein coding gene Chr11:113420724-113429325 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019686
 protein coding gene Chr11:105197005-105205233 (+)
PWK/PhJ MGP_PWKPhJ_G0018325
 protein coding gene Chr11:102254250-102261070 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018117
 protein coding gene Chr11:104950146-104957729 (+)
WSB/EiJ MGP_WSBEiJ_G0018611
 protein coding gene Chr11:105193324-105201368 (+)



Homology
more
  • Human Ortholog
    HEXIM2, HEXIM P-TEFb complex subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HEXIM2, HEXIM P-TEFb complex subunit 2
  • Synonyms
    L3
  • Links
    NCBI Gene ID: 124790
    neXtProt AC: NX_Q96MH2
    UniProt: Q96MH2

  • Chr Location
    17q21.31; chr17:45160174-45170040 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    2
  • cDNA Data
    15
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043372 Ensembl Gene Model | MGI Sequence Detail 7448 C57BL/6J ±  kb
transcript ENSMUST00000107037 Ensembl | MGI Sequence Detail 1221 Not Applicable  
polypeptide ENSMUSP00000102652 Ensembl | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:191206 Okamura D, et al., Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells. Genes Dev. 2012 Nov 15;26(22):2477-82
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory