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Eif3j1 Gene Detail
Summary
  • Symbol
    Eif3j1
  • Name
    eukaryotic translation initiation factor 3, subunit J1
  • Synonyms
    1810016I04Rik, 2700079K05Rik, eIF3-alpha, Eif3j, eIF3-p35, Eif3s1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925905
    NCBI Gene: 78655
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:121859061-121884113 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.49 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    570 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925905
 protein coding gene Chr2:121859027-121887079 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026402
 protein coding gene Chr2:125004458-125035410 (+)
A/J MGP_AJ_G0026364
 protein coding gene Chr2:119893807-119923438 (+)
AKR/J MGP_AKRJ_G0026341
 protein coding gene Chr2:123259106-123286583 (+)
BALB/cJ MGP_BALBcJ_G0026376
 protein coding gene Chr2:120121940-120151701 (+)
C3H/HeJ MGP_C3HHeJ_G0026122
 protein coding gene Chr2:123737089-123762944 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026824
 protein coding gene Chr2:129063745-129096179 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024201
 protein coding gene Chr2:114874585-114902351 (+)
CAST/EiJ MGP_CASTEiJ_G0025583
 protein coding gene Chr2:124071640-124102422 (+)
CBA/J MGP_CBAJ_G0026100
 protein coding gene Chr2:133600631-133647830 (+)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0026199
 protein coding gene Chr2:118089090-118116373 (+)
LP/J MGP_LPJ_G0026339
 protein coding gene Chr2:125250969-125282971 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026219
 protein coding gene Chr2:137829923-137860117 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026878
 protein coding gene Chr2:123369272-123396766 (+)
PWK/PhJ MGP_PWKPhJ_G0025319
 protein coding gene Chr2:118904424-118933121 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0025655
 protein coding gene Chr2:124227258-124260120 (+)



Homology
more
  • Human Ortholog
    EIF3J, eukaryotic translation initiation factor 3 subunit J
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF3J, eukaryotic translation initiation factor 3 subunit J
  • Synonyms
    eIF3-alpha, eIF3-p35, EIF3S1
  • Links
    NCBI Gene ID: 8669
    neXtProt AC: NX_O75822
    UniProt: O75822

  • Chr Location
    15q21.1; chr15:44537125-44563029 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    9
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Eif3j1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78655 NCBI Gene Model | MGI Sequence Detail 25053 C57BL/6J ±  kb
transcript NM_144545 RefSeq | MGI Sequence Detail 2434 ZRU/MplStud  
polypeptide Q3UGC7 UniProt | EBI | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000035847 eukaryotic translation initiation factor 3 subunit J-A
    (term hierarchy)
  • GlyGen
    Q3UGC7 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 5
Other
Accession IDs
less
MGI:1925620, MGI:2138762, MGI:2138769, MGI:2139474
References
more
  • Summaries
    All 36
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:183559 Xu TR, et al., Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway. Mol Cell Biol. 2012 Jan;32(1):88-95
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory