About   Help   FAQ
Lrrc58 Gene Detail
Summary
  • Symbol
    Lrrc58
  • Name
    leucine rich repeat containing 58
  • Synonyms
    1810012N18Rik, C330018J07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443542
    NCBI Gene: 320184
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:37688762-37709219 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 26.49 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    527 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443542
 protein coding gene Chr16:37688751-37709220 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022806
 protein coding gene Chr16:36357164-36388568 (+)
A/J MGP_AJ_G0022771
 protein coding gene Chr16:34547872-34568927 (+)
AKR/J MGP_AKRJ_G0022743
 protein coding gene Chr16:35873334-35891409 (+)
BALB/cJ MGP_BALBcJ_G0022772
 protein coding gene Chr16:34673975-34694748 (+)
C3H/HeJ MGP_C3HHeJ_G0022536
 protein coding gene Chr16:35978411-35999168 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023219
 protein coding gene Chr16:37205914-37227733 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020733
 protein coding gene Chr16:34932173-34949510 (+)
CAST/EiJ MGP_CASTEiJ_G0022062
 protein coding gene Chr16:36123076-36146809 (+)
CBA/J MGP_CBAJ_G0022507
 protein coding gene Chr16:38824010-38852196 (+)
DBA/2J MGP_DBA2J_G0022639
 protein coding gene Chr16:34441231-34462083 (+)
FVB/NJ MGP_FVBNJ_G0022614
 protein coding gene Chr16:34473498-34494946 (+)
LP/J MGP_LPJ_G0022707
 protein coding gene Chr16:36044990-36065433 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022633
 protein coding gene Chr16:37970805-37989411 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023234
 protein coding gene Chr16:35824362-35840216 (+)
PWK/PhJ MGP_PWKPhJ_G0021802
 protein coding gene Chr16:34845843-34866526 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021633
 protein coding gene Chr16:35739767-35767081 (+)
WSB/EiJ MGP_WSBEiJ_G0022106
 protein coding gene Chr16:35903832-35926613 (+)



Homology
more
  • Human Ortholog
    LRRC58, leucine rich repeat containing 58
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC58, leucine rich repeat containing 58
  • Links
    NCBI Gene ID: 116064
    neXtProt AC: NX_Q96CX6
    UniProt: Q96CX6

  • Chr Location
    3q13.33; chr3:120324509-120349354 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    272
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320184 NCBI Gene Model | MGI Sequence Detail 20458 C57BL/6J ±  kb
transcript NM_177093 RefSeq | MGI Sequence Detail 8592 C57BL/6  
polypeptide Q3UGP9 UniProt | EBI | MGI Sequence Detail 366 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032188 leucine-rich repeat-containing protein 58
    (term hierarchy)
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR050715 Leucine-rich repeat and signaling effector domain-containing protein
    IPR050216 Leucine-rich repeat domain-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
  • GlyGen
    Q3UGP9 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 272
    cDNA 272

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916360
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory