Tedc1 MGI Mouse Gene Detail - MGI:2144738 - tubulin epsilon and delta complex 1

Symbol

Tedc1
Name

tubulin epsilon and delta complex 1
Synonyms

4930427A07Rik

Feature Type

protein coding gene
IDs

MGI:2144738
NCBI Gene: 104732
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr12:113120041-113129668 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 61.62 cM
Mapping Data

2 experiments

SNPs within 2kb

14 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2144738	protein coding gene	Chr12:113118639-113135102 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020174	protein coding gene	Chr12:115652464-115662257 (+)
A/J	MGP_AJ_G0020130	protein coding gene	Chr12:111174604-111184224 (+)
AKR/J	MGP_AKRJ_G0020105	protein coding gene	Chr12:114405822-114415592 (+)
BALB/cJ	MGP_BALBcJ_G0020115	protein coding gene	Chr12:111640122-111649934 (+)
C3H/HeJ	MGP_C3HHeJ_G0019917	protein coding gene	Chr12:114927768-114937568 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020560	protein coding gene	Chr12:119197836-119207458 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018174	protein coding gene	Chr12:107608707-107618186 (+)
CAST/EiJ	MGP_CASTEiJ_G0019457	protein coding gene	Chr12:109774584-109784438 (+)
CBA/J	MGP_CBAJ_G0019884	protein coding gene	Chr12:123765783-123775588 (+)
DBA/2J	MGP_DBA2J_G0020001	protein coding gene	Chr12:110675725-110685306 (+)
FVB/NJ	MGP_FVBNJ_G0019986	protein coding gene	Chr12:109519366-109528948 (+)
LP/J	MGP_LPJ_G0020075	protein coding gene	Chr12:115472795-115482403 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020024	protein coding gene	Chr12:126853691-126863308 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020589	protein coding gene	Chr12:113922516-113932340 (+)
PWK/PhJ	MGP_PWKPhJ_G0019219	protein coding gene	Chr12:105337657-105347477 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019023	protein coding gene	Chr12:108102952-108117050 (+)
WSB/EiJ	MGP_WSBEiJ_G0019517	protein coding gene	Chr12:114836762-114846578 (+)

Human Ortholog

TEDC1, tubulin epsilon and delta complex 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TEDC1, tubulin epsilon and delta complex 1
Synonyms

C14orf80
Links

HGNC:20127

NCBI Gene ID: 283643

neXtProt AC: NX_Q86SX3

UniProt: Q86SX3
Chr Location

14q32.33; chr14:105489855-105499575 (+) GRCh38

MGI Vertebrate Homology

Tedc1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TEDC1
Gene Tree

Tedc1

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Phenotype Summary

10 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

18
Endonuclease-mediated

2
Gene trapped

13
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

27 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

2
cDNA Data

47
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

60
RefSeq

6
UniProt

6
CCDS

CCDS49196.1

Ensembl

ENSMUSG00000037466 (Evidence)
NCBI Gene

104732

			Length	Strain/Species	Flank
genomic	ENSMUSG00000037466	Ensembl Gene Model \| MGI Sequence Detail	9628	C57BL/6J	± kb
transcript	ENSMUST00000049271	Ensembl \| MGI Sequence Detail	2441	Not Applicable
polypeptide	ENSMUSP00000035351	Ensembl \| MGI Sequence Detail	420	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000036975 tubulin epsilon and delta complex protein 1

(term hierarchy)
InterPro Domains

IPR043535 Tubulin epsilon and delta complex protein 1

IPR027996 Tubulin epsilon and delta complex protein 1 domain

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All nucleic 47

cDNA 47

Microarray probesets 4

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MGI:5904755

Summaries

All 36

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 12
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tedc1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr115493	Chr12:113120023-113120062 (+)	2 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/22/2024 MGI 6.24