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Rmi2 Gene Detail
Summary
  • Symbol
    Rmi2
  • Name
    RecQ mediated genome instability 2
  • Synonyms
    A630055G03Rik, LOC381034
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685383
    NCBI Gene: 223970
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10652923-10661099 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 6.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    294 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685383
 protein coding gene Chr16:10652923-10710830 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022517
 protein coding gene Chr16:7665928-7729155 (+)
A/J MGP_AJ_G0022479
 protein coding gene Chr16:7246880-7304011 (+)
AKR/J MGP_AKRJ_G0022455
 protein coding gene Chr16:7571112-7638232 (+)
BALB/cJ MGP_BALBcJ_G0022483
 protein coding gene Chr16:7375565-7434403 (+)
C3H/HeJ MGP_C3HHeJ_G0022250
 protein coding gene Chr16:7653214-7715495 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022932
 protein coding gene Chr16:7824960-7886021 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020452
 protein coding gene Chr16:7390206-7448676 (+)
CAST/EiJ MGP_CASTEiJ_G0021777
 protein coding gene Chr16:7671639-7732644 (+)
CBA/J MGP_CBAJ_G0022219
 protein coding gene Chr16:8161156-8237062 (+)
DBA/2J MGP_DBA2J_G0022350
 protein coding gene Chr16:7248123-7309117 (+)
FVB/NJ MGP_FVBNJ_G0022326
 protein coding gene Chr16:7235124-7293854 (+)
LP/J MGP_LPJ_G0022418
 protein coding gene Chr16:7615519-7682009 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022348
 protein coding gene Chr16:7872491-7937830 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022945
 protein coding gene Chr16:7522803-7582808 (+)
PWK/PhJ MGP_PWKPhJ_G0021517
 protein coding gene Chr16:7460298-7524858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021347
 protein coding gene Chr16:7582870-7646936 (+)
WSB/EiJ MGP_WSBEiJ_G0021825
 protein coding gene Chr16:7599876-7670056 (+)



Homology
more
  • Human Ortholog
    RMI2, RecQ mediated genome instability 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RMI2, RecQ mediated genome instability 2
  • Synonyms
    BLAP18, C16orf75
  • Links
    NCBI Gene ID: 116028
    neXtProt AC: NX_Q96E14
    UniProt: Q96E14

  • Chr Location
    16p13.13; chr16:11249619-11381662 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    4
  • cDNA Data
    6
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223970 NCBI Gene Model | MGI Sequence Detail 8177 C57BL/6J ±  kb
transcript NM_001162932 RefSeq | MGI Sequence Detail 3739 C57BL/6  
polypeptide Q3UPE3 UniProt | EBI | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685775
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:319969 Xue X, et al., Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIalpha-RMI1-RMI2 protein complex. J Biol Chem. 2013 May 17;288(20):14221-14227
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory