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Lsmem1 Gene Detail
Summary
  • Symbol
    Lsmem1
  • Name
    leucine-rich single-pass membrane protein 1
  • Synonyms
    Gm889, LOC380755
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685735
    NCBI Gene: 380755
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:40226385-40249314 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 18.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    707 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685735
 protein coding gene Chr12:40225492-40249489 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019701
 protein coding gene Chr12:38590367-38611891 (-)
A/J MGP_AJ_G0019667
 protein coding gene Chr12:37323251-37345503 (-)
AKR/J MGP_AKRJ_G0019638
 protein coding gene Chr12:38450394-38473522 (-)
BALB/cJ MGP_BALBcJ_G0019645
 protein coding gene Chr12:37540074-37560187 (-)
C3H/HeJ MGP_C3HHeJ_G0019449
 protein coding gene Chr12:38388818-38410960 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020092
 protein coding gene Chr12:39752449-39776270 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017717
 protein coding gene Chr12:36461042-36476169 (-)
CAST/EiJ MGP_CASTEiJ_G0019002
 protein coding gene Chr12:33575751-33596573 (-)
CBA/J MGP_CBAJ_G0019421
 protein coding gene Chr12:41095753-41128564 (-)
DBA/2J MGP_DBA2J_G0019534
 protein coding gene Chr12:37184720-37202434 (-)
FVB/NJ MGP_FVBNJ_G0019523
 protein coding gene Chr12:36816656-36832456 (-)
LP/J MGP_LPJ_G0019604
 protein coding gene Chr12:38575857-38595890 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019559
 protein coding gene Chr12:41254379-41284159 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020132
 protein coding gene Chr12:38012075-38032654 (-)
PWK/PhJ MGP_PWKPhJ_G0018769
 protein coding gene Chr12:31862419-31879960 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018559
 protein coding gene Chr12:32666018-32687210 (-)
WSB/EiJ MGP_WSBEiJ_G0019052
 protein coding gene Chr12:38322449-38340348 (-)



Homology
more
  • Human Ortholog
    LSMEM1, leucine rich single-pass membrane protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LSMEM1, leucine rich single-pass membrane protein 1
  • Synonyms
    C7orf53
  • Links
    NCBI Gene ID: 286006
    neXtProt AC: NX_Q8N8F7
    UniProt: Q8N8F7

  • Chr Location
    7q31.1; chr7:112480304-112491062 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380755 NCBI Gene Model | MGI Sequence Detail 22930 C57BL/6J ±  kb
transcript NM_001033437 RefSeq | MGI Sequence Detail 1213 C57BL/6  
polypeptide Q3UQS2 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory