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Ncbp1 Gene Detail
Summary
  • Symbol
    Ncbp1
  • Name
    nuclear cap binding protein subunit 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891840
    NCBI Gene: 433702
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:46138732-46172403 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 24.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    824 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891840
 protein coding gene Chr4:46138613-46172403 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028253
 protein coding gene Chr4:44420181-44455661 (+)
A/J MGP_AJ_G0028212
 protein coding gene Chr4:42811760-42845466 (+)
AKR/J MGP_AKRJ_G0028162
 protein coding gene Chr4:43848340-43883567 (+)
BALB/cJ MGP_BALBcJ_G0028232
 protein coding gene Chr4:42908952-42942685 (+)
C3H/HeJ MGP_C3HHeJ_G0027953
 protein coding gene Chr4:44451794-44491947 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028673
 protein coding gene Chr4:46066932-46102558 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025982
 protein coding gene Chr4:40201740-40235745 (+)
CAST/EiJ MGP_CASTEiJ_G0027392
 protein coding gene Chr4:44014313-44048974 (+)
CBA/J MGP_CBAJ_G0027919
 protein coding gene Chr4:47518608-47558101 (+)
DBA/2J MGP_DBA2J_G0028069
 protein coding gene Chr4:42705825-42739976 (+)
FVB/NJ MGP_FVBNJ_G0028036
 protein coding gene Chr4:41948584-41982228 (+)
LP/J MGP_LPJ_G0028168
 protein coding gene Chr4:44476840-44511649 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028060
 protein coding gene Chr4:50624360-50658955 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028708
 protein coding gene Chr4:44066333-44102345 (+)
PWK/PhJ MGP_PWKPhJ_G0027117
 protein coding gene Chr4:42793974-42828437 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026945
 protein coding gene Chr4:43559907-43598439 (+)
WSB/EiJ MGP_WSBEiJ_G0027470
 protein coding gene Chr4:43968567-44003602 (+)



Homology
more
  • Human Ortholog
    NCBP1, nuclear cap binding protein subunit 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NCBP1, nuclear cap binding protein subunit 1
  • Synonyms
    CBP80, NCBP, Sto1
  • Links
    NCBI Gene ID: 4686
    neXtProt AC: NX_Q09161
    UniProt: Q09161

  • Chr Location
    9q22.33; chr9:97633668-97673748 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    71
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 433702 NCBI Gene Model | MGI Sequence Detail 33672 C57BL/6J ±  kb
transcript NM_001033201 RefSeq | MGI Sequence Detail 2876 C57BL/6  
polypeptide Q3UYV9 UniProt | EBI | MGI Sequence Detail 790 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140419, MGI:2140583
References
more
  • Summaries
    All 43
    Developmental Gene Expression 1
    Gene Ontology 16
    Phenotypes 8
  • Earliest
    J:34628 Chadwick BP, et al., Nuclear cap binding protein maps close to the xeroderma pigmentosum complementation group A (XPA) locus in human and mouse. Genomics. 1996 1;35(3):632-3
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory