About   Help   FAQ
Sel1l2 Gene Detail
Summary
  • Symbol
    Sel1l2
  • Name
    sel-1 suppressor of lin-12-like 2 (C. elegans)
  • Synonyms
    LOC228684
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684964
    NCBI Gene: 228684
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:140071775-140231626 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 69.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4473 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684964
 protein coding gene Chr2:140071519-140231644 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026570
 protein coding gene Chr2:144159216-144323091 (-)
A/J MGP_AJ_G0026534
 protein coding gene Chr2:138336181-138487187 (-)
AKR/J MGP_AKRJ_G0026508
 protein coding gene Chr2:142285995-142449802 (-)
BALB/cJ MGP_BALBcJ_G0026546
 protein coding gene Chr2:138727927-138891734 (-)
C3H/HeJ MGP_C3HHeJ_G0026289
 protein coding gene Chr2:142814551-142972906 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026991
 protein coding gene Chr2:148504474-148669525 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024367
 protein coding gene Chr2:132644923-132799847 (-)
CAST/EiJ MGP_CASTEiJ_G0025750
 protein coding gene Chr2:143118940-143284855 (-)
CBA/J MGP_CBAJ_G0026269
 protein coding gene Chr2:153929152-154098888 (-)
DBA/2J MGP_DBA2J_G0026403
 protein coding gene Chr2:137667196-137818698 (-)
FVB/NJ MGP_FVBNJ_G0026367
 protein coding gene Chr2:136223395-136378698 (-)
LP/J MGP_LPJ_G0026507
 protein coding gene Chr2:144311428-144465117 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026387
 protein coding gene Chr2:157957325-158135515 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027046
 protein coding gene Chr2:142267156-142428261 (-)
PWK/PhJ MGP_PWKPhJ_G0025486
 protein coding gene Chr2:137243777-137401442 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025287
 protein coding gene Chr2:141351922-141500802 (-)
WSB/EiJ MGP_WSBEiJ_G0025823
 protein coding gene Chr2:143242620-143420831 (-)



Homology
more
  • Human Ortholog
    SEL1L2, SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SEL1L2, SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase
  • Synonyms
    C20orf50, sel-1L2
  • Links
    NCBI Gene ID: 80343
    neXtProt AC: NX_Q5TEA6
    UniProt: Q5TEA6

  • Chr Location
    20p12.1; chr20:13849247-13996443 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074764 Ensembl Gene Model | MGI Sequence Detail 159852 C57BL/6J ±  kb
transcript ENSMUST00000122367 Ensembl | MGI Sequence Detail 2216 Not Applicable  
polypeptide ENSMUSP00000113800 Ensembl | MGI Sequence Detail 688 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory