Olfml2b MGI Mouse Gene Detail - MGI:2443310

Symbol

Olfml2b
Name

olfactomedin-like 2B
Synonyms

1110018N05Rik, 4832415H08Rik, photomedin-2

Feature Type

protein coding gene
IDs

MGI:2443310
NCBI Gene: 320078
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr1:170472101-170510356 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 76.95 cM
Mapping Data

2 experiments

SNPs within 2kb

1309 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443310	protein coding gene	Chr1:170472101-170510358 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016732	protein coding gene	Chr1:176371106-176410517 (+)
A/J	MGP_AJ_G0016712	protein coding gene	Chr1:169183945-169222121 (+)
AKR/J	MGP_AKRJ_G0016678	protein coding gene	Chr1:174244235-174282487 (+)
BALB/cJ	MGP_BALBcJ_G0016673	protein coding gene	Chr1:169651691-169690728 (+)
C3H/HeJ	MGP_C3HHeJ_G0016496	protein coding gene	Chr1:174500817-174540412 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017134	protein coding gene	Chr1:182201516-182239757 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014843	protein coding gene	Chr1:160896094-160935251 (+)
CAST/EiJ	MGP_CASTEiJ_G0016077	protein coding gene	Chr1:174136060-174174150 (+)
CBA/J	MGP_CBAJ_G0016471	protein coding gene	Chr1:188697562-188736018 (+)
DBA/2J	MGP_DBA2J_G0016578	protein coding gene	Chr1:168033163-168071413 (+)
FVB/NJ	MGP_FVBNJ_G0016575	protein coding gene	Chr1:166393973-166432503 (+)
LP/J	MGP_LPJ_G0016649	protein coding gene	Chr1:177491054-177530101 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016601	protein coding gene	Chr1:196021164-196059392 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017171	protein coding gene	Chr1:174154674-174192837 (+)
PWK/PhJ	MGP_PWKPhJ_G0015863	protein coding gene	Chr1:167272623-167311116 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015647	protein coding gene	Chr1:172901101-172938004 (+)
WSB/EiJ	MGP_WSBEiJ_G0016139	protein coding gene	Chr1:174269396-174307586 (+)

Human Ortholog

OLFML2B, olfactomedin like 2B

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

OLFML2B, olfactomedin like 2B
Links

HGNC:24558

NCBI Gene ID: 25903

neXtProt AC: NX_Q68BL8

UniProt: Q68BL8
Chr Location

1q23.3; chr1:161983192-162023869 (-) GRCh38

MGI Vertebrate Homology

Olfml2b stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: OLFML2B
Gene Tree

Olfml2b

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Chemically induced (other)

2
Endonuclease-mediated

1
Targeted

2
Genomic Mutations

2 involving Olfml2b
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

37 strains or lines available

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All GO Annotations

7
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

919
Tissues

30
cDNA Data

33
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

GEISHA OLFML2B

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All Sequences

60
RefSeq

24
UniProt

2
CCDS

CCDS15473.1

Ensembl

ENSMUSG00000038463 (Evidence)
NCBI Gene

320078

			Length	Strain/Species	Flank
genomic	320078	NCBI Gene Model \| MGI Sequence Detail	38256	C57BL/6J	± kb
transcript	NM_001404308	RefSeq \| MGI Sequence Detail	3609	C57BL/6
polypeptide	Q3V1G4	UniProt \| EBI \| MGI Sequence Detail	746	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000011629 olfactomedin-like protein 2B

(term hierarchy)
InterPro Domains

IPR003112 Olfactomedin-like domain

IPR050605 Olfactomedin-like domain-containing protein
GlyGen

Q3V1G4 3 sites, 1 N-linked glycan (2 sites)

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All nucleic 33

cDNA 33

Microarray probesets 5

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MGI:1915832, MGI:2138272

Summaries

All 33

Developmental Gene Expression 2

Gene Ontology 4

Phenotypes 7
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Olfml2b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr9927	Chr1:170470409-170470420 (+)	-1,686 bp
Tssr9928	Chr1:170472018-170472027 (+)	-78 bp
Tssr9929	Chr1:170472059-170472083 (+)	-30 bp
Tssr9930	Chr1:170472092-170472139 (+)	15 bp
Tssr9931	Chr1:170472141-170472155 (+)	47 bp
Tssr9932	Chr1:170472158-170472171 (+)	64 bp
Tssr9933	Chr1:170472354-170472406 (+)	279 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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