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Srbd1 Gene Detail
Summary
  • Symbol
    Srbd1
  • Name
    S1 RNA binding domain 1
  • Synonyms
    D530025C17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925836
    NCBI Gene: 78586
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:86292093-86452603 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 56.51 cM, cytoband E4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3905 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925836
 protein coding gene Chr17:86292093-86452644 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024090
 protein coding gene Chr17:89281184-89449256 (-)
A/J MGP_AJ_G0024049
 protein coding gene Chr17:86410573-86572144 (-)
AKR/J MGP_AKRJ_G0024018
 protein coding gene Chr17:87821713-87987806 (-)
BALB/cJ MGP_BALBcJ_G0024050
 protein coding gene Chr17:86254309-86420112 (-)
C3H/HeJ MGP_C3HHeJ_G0023815
 protein coding gene Chr17:88705822-88875134 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024495
 protein coding gene Chr17:92389795-92567080 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021934
 protein coding gene Chr17:81591913-81756982 (-)
CAST/EiJ MGP_CASTEiJ_G0023294
 protein coding gene Chr17:89512672-89683808 (-)
CBA/J MGP_CBAJ_G0023789
 protein coding gene Chr17:96240462-96417924 (-)
DBA/2J MGP_DBA2J_G0023917
 protein coding gene Chr17:84864803-85028814 (-)
FVB/NJ MGP_FVBNJ_G0023883
 protein coding gene Chr17:84364838-84524673 (-)
LP/J MGP_LPJ_G0024001
 protein coding gene Chr17:90039145-90209024 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023911
 protein coding gene Chr17:96228101-96397814 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024540
 protein coding gene Chr17:88348738-88512586 (-)
PWK/PhJ MGP_PWKPhJ_G0023039
 protein coding gene Chr17:84479598-84642205 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022850
 protein coding gene Chr17:85133347-85298316 (-)
WSB/EiJ MGP_WSBEiJ_G0023360
 protein coding gene Chr17:89198657-89368571 (-)



Homology
more
  • Human Ortholog
    SRBD1, S1 RNA binding domain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRBD1, S1 RNA binding domain 1
  • Links
    NCBI Gene ID: 55133
    neXtProt AC: NX_Q8N5C6
    UniProt: Q8N5C6

  • Chr Location
    2p21; chr2:45388680-45612165 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    2
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024135 Ensembl Gene Model | MGI Sequence Detail 160511 C57BL/6J ±  kb
transcript ENSMUST00000095187 Ensembl | MGI Sequence Detail 3530 Not Applicable  
polypeptide ENSMUSP00000092810 Ensembl | MGI Sequence Detail 981 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146870, MGI:2147143
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory