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Spsb3 Gene Detail
Summary
  • Symbol
    Spsb3
  • Name
    splA/ryanodine receptor domain and SOCS box containing 3
  • Synonyms
    2310012N15Rik, 3300001M01Rik, SSB3, Tce1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891471
    NCBI Gene: 79043
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:25105617-25111126 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    194 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891471
 protein coding gene Chr17:25104956-25111126 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023328
 protein coding gene Chr17:23912140-23917482 (+)
A/J MGP_AJ_G0023288
 protein coding gene Chr17:23248896-23254271 (+)
AKR/J MGP_AKRJ_G0023255
 protein coding gene Chr17:23337428-23342770 (+)
BALB/cJ MGP_BALBcJ_G0023293
 protein coding gene Chr17:23449387-23454813 (+)
C3H/HeJ MGP_C3HHeJ_G0023053
 protein coding gene Chr17:23702026-23708108 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023736
 protein coding gene Chr17:24974953-24980462 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021211
 protein coding gene Chr17:20709097-20714466 (+)
CAST/EiJ MGP_CASTEiJ_G0022555
 protein coding gene Chr17:23557271-23562648 (+)
CBA/J MGP_CBAJ_G0023029
 protein coding gene Chr17:25816316-25824871 (+)
DBA/2J MGP_DBA2J_G0023158
 protein coding gene Chr17:22841556-22847108 (+)
FVB/NJ MGP_FVBNJ_G0023128
 protein coding gene Chr17:22562090-22567465 (+)
LP/J MGP_LPJ_G0023235
 protein coding gene Chr17:24217392-24222745 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023147
 protein coding gene Chr17:25508784-25514159 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023774
 protein coding gene Chr17:23621900-23627275 (+)
PWK/PhJ MGP_PWKPhJ_G0022304
 protein coding gene Chr17:21596944-21602420 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022122
 protein coding gene Chr17:21686137-21691587 (+)
WSB/EiJ MGP_WSBEiJ_G0022618
 protein coding gene Chr17:23694535-23699844 (+)



Homology
more
  • Human Ortholog
    SPSB3, splA/ryanodine receptor domain and SOCS box containing 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPSB3, splA/ryanodine receptor domain and SOCS box containing 3
  • Synonyms
    C16orf31, SSB3
  • Links
    NCBI Gene ID: 90864
    neXtProt AC: NX_Q6PJ21
    UniProt: Q6PJ21

  • Chr Location
    16p13.3; chr16:1776712-1793700 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024160 Ensembl Gene Model | MGI Sequence Detail 5510 C57BL/6J ±  kb
transcript ENSMUST00000024976 Ensembl | MGI Sequence Detail 1947 Not Applicable  
polypeptide ENSMUSP00000024976 Ensembl | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:1914174, MGI:1916872
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:63450 Kargul GJ, et al., Eleven densely clustered genes, six of them novel, in 176 kb of mouse t-complex DNA. Genome Res. 2000 Jul;10(7):916-23
  • Latest
    J:232438 Ohmura S, et al., Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs. J Clin Invest. 2016 Mar 1;126(3):865-78
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory