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Tsr3 Gene Detail
Summary
  • Symbol
    Tsr3
  • Name
    TSR3 20S rRNA accumulation
  • Synonyms
    0610007P22Rik, 1110014B11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915577
    NCBI Gene: 68327
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:25459141-25461773 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915577
 protein coding gene Chr17:25459120-25461773 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023346
 protein coding gene Chr17:24291010-24293623 (+)
A/J MGP_AJ_G0023305
 protein coding gene Chr17:23610779-23613400 (+)
AKR/J MGP_AKRJ_G0023271
 protein coding gene Chr17:23701710-23704323 (+)
BALB/cJ MGP_BALBcJ_G0023310
 protein coding gene Chr17:23809328-23811941 (+)
C3H/HeJ MGP_C3HHeJ_G0023070
 protein coding gene Chr17:24077866-24081761 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023752
 protein coding gene Chr17:25354255-25356883 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021228
 protein coding gene Chr17:21073232-21075873 (+)
CAST/EiJ MGP_CASTEiJ_G0022572
 protein coding gene Chr17:23926870-23930899 (+)
CBA/J MGP_CBAJ_G0023045
 protein coding gene Chr17:26216811-26219424 (+)
DBA/2J MGP_DBA2J_G0023175
 protein coding gene Chr17:23196163-23198784 (+)
FVB/NJ MGP_FVBNJ_G0023145
 protein coding gene Chr17:22925880-22928493 (+)
LP/J MGP_LPJ_G0023252
 protein coding gene Chr17:24583623-24586236 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023164
 protein coding gene Chr17:25878296-25880917 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023792
 protein coding gene Chr17:23988185-23990806 (+)
PWK/PhJ MGP_PWKPhJ_G0022321
 protein coding gene Chr17:21960040-21962789 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022139
 protein coding gene Chr17:22060658-22065997 (+)
WSB/EiJ MGP_WSBEiJ_G0022635
 protein coding gene Chr17:24062783-24065404 (+)



Homology
more
  • Human Ortholog
    TSR3, TSR3 ribosome maturation factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSR3, TSR3 ribosome maturation factor
  • Synonyms
    C16orf42, HsTsr3
  • Links
    NCBI Gene ID: 115939
    neXtProt AC: NX_Q9UJK0
    UniProt: Q9UJK0

  • Chr Location
    16p13.3; chr16:1349240-1351878 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    34
  • cDNA Data
    12
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015126 Ensembl Gene Model | MGI Sequence Detail 2633 C57BL/6J ±  kb
transcript ENSMUST00000249831 Ensembl | MGI Sequence Detail 1219 Not Applicable  
polypeptide ENSMUSP00000159936 Ensembl | MGI Sequence Detail 366 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    16 Sequences
  • Protein Ontology
    PR:000030855 18S rRNA aminocarboxypropyltransferase
    (term hierarchy)
  • EC
    2.5.1.157
  • InterPro Domains
    IPR022968 16S/18S rRNA aminocarboxypropyltransferase Tsr3
    IPR007177 16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal
    IPR007209 RNase L inhibitor RLI-like, possible metal-binding domain
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:1926015, MGI:2142654
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory