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Zdhhc18 Gene Detail
Summary
  • Symbol
    Zdhhc18
  • Name
    zinc finger, DHHC domain containing 18
  • Feature Type
    protein coding gene
  • IDs
    MGI:3527792
    NCBI Gene: 503610
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:133331969-133360801 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 66.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1008 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3527792
 protein coding gene Chr4:133331969-133377465 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028902
 protein coding gene Chr4:135888354-135940239 (-)
A/J MGP_AJ_G0028861
 protein coding gene Chr4:130187642-130231485 (-)
AKR/J MGP_AKRJ_G0028813
 protein coding gene Chr4:133891284-133935502 (-)
BALB/cJ MGP_BALBcJ_G0028884
 protein coding gene Chr4:130821498-130872776 (-)
C3H/HeJ MGP_C3HHeJ_G0028598
 protein coding gene Chr4:134143950-134192459 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029326
 protein coding gene Chr4:140751616-140798357 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026597
 protein coding gene Chr4:123252411-123280763 (-)
CAST/EiJ MGP_CASTEiJ_G0028031
 protein coding gene Chr4:132256813-132302521 (-)
CBA/J MGP_CBAJ_G0028563
 protein coding gene Chr4:144446435-144495685 (-)
DBA/2J MGP_DBA2J_G0028712
 protein coding gene Chr4:130610784-130654921 (-)
FVB/NJ MGP_FVBNJ_G0028680
 protein coding gene Chr4:129496508-129546616 (-)
LP/J MGP_LPJ_G0028813
 protein coding gene Chr4:135999408-136044095 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028705
 protein coding gene Chr4:148941202-148990826 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029364
 protein coding gene Chr4:134311734-134357468 (-)
PWK/PhJ MGP_PWKPhJ_G0027751
 protein coding gene Chr4:127324477-127370220 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027577
 protein coding gene Chr4:130134121-130188876 (-)
WSB/EiJ MGP_WSBEiJ_G0028110
 protein coding gene Chr4:134495313-134540006 (-)



Homology
more
  • Human Ortholog
    ZDHHC18, zinc finger DHHC-type palmitoyltransferase 18
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZDHHC18, zinc finger DHHC-type palmitoyltransferase 18
  • Synonyms
    DHHC-18, DHHC18
  • Links
    NCBI Gene ID: 84243
    neXtProt AC: NX_Q9NUE0
    UniProt: Q9NUE0

  • Chr Location
    1p36.11; chr1:26826688-26857604 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 503610 NCBI Gene Model | MGI Sequence Detail 28833 C57BL/6J ±  kb
transcript NM_001017968 RefSeq | MGI Sequence Detail 2847 C57BL/6  
polypeptide Q5Y5T2 UniProt | EBI | MGI Sequence Detail 380 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Gene Ontology 7
    Phenotypes 18
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:344900 Shi C, et al., ZDHHC18 negatively regulates cGAS-mediated innate immunity through palmitoylation. EMBO J. 2022 Jun 1;41(11):e109272
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory