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Dbp Gene Detail
Summary
  • Symbol
    Dbp
  • Name
    D site albumin promoter binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:94866
    NCBI Gene: 13170
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr7:45354658-45359579 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.45 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    128 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_94866
 protein coding gene Chr7:45354512-45359627 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032241
 protein coding gene Chr7:46013651-46018716 (+)
A/J MGP_AJ_G0032220
 protein coding gene Chr7:45101058-45106125 (+)
AKR/J MGP_AKRJ_G0032156
 protein coding gene Chr7:46353155-46358222 (+)
BALB/cJ MGP_BALBcJ_G0032232
 protein coding gene Chr7:45095806-45100873 (+)
C3H/HeJ MGP_C3HHeJ_G0031947
 protein coding gene Chr7:46847412-46852477 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032724
 protein coding gene Chr7:48264267-48269334 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029738
 protein coding gene Chr7:47655094-47660188 (+)
CAST/EiJ MGP_CASTEiJ_G0031276
 protein coding gene Chr7:38287674-38292740 (+)
CBA/J MGP_CBAJ_G0031912
 protein coding gene Chr7:49874022-49879089 (+)
DBA/2J MGP_DBA2J_G0032070
 protein coding gene Chr7:44781682-44786747 (+)
FVB/NJ MGP_FVBNJ_G0032021
 protein coding gene Chr7:44554368-44559435 (+)
LP/J MGP_LPJ_G0032148
 protein coding gene Chr7:46718314-46723381 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032058
 protein coding gene Chr7:48554992-48560059 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032740
 protein coding gene Chr7:45564382-45569450 (+)
PWK/PhJ MGP_PWKPhJ_G0030998
 protein coding gene Chr7:38148596-38153660 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030836
 protein coding gene Chr7:33595165-33600230 (+)
WSB/EiJ MGP_WSBEiJ_G0031393
 protein coding gene Chr7:46068666-46073733 (+)



Homology
more
  • Human Ortholog
    DBP, D-box binding PAR bZIP transcription factor
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DBP, D-box binding PAR bZIP transcription factor
  • Synonyms
    DABP, taxREB302
  • Links
    NCBI Gene ID: 1628
    neXtProt AC: NX_Q10586
    UniProt: Q10586

  • Chr Location
    19q13.33; chr19:48630030-48637379 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DBP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    16 phenotypes from multigenic genotypes
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display a shortened circadian period and decreased acvtivity during the dark phase.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1014
  • Tissues
    141
  • cDNA Data
    9
  • Literature Summary
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13170 NCBI Gene Model | MGI Sequence Detail 4922 C57BL/6J ±  kb
transcript NM_016974 RefSeq | MGI Sequence Detail 1643 ZRU/MplStud  
polypeptide Q60925 UniProt | EBI | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 2
    cDNA 10
    Primer pair 4
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-8803
References
more
  • Summaries
    All 83
    Developmental Gene Expression 15
    Gene Ontology 5
    Phenotypes 24
  • Earliest
    J:81277 Drolet DW, et al., TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. Genes Dev. 1991 Oct;5(10):1739-53
  • Latest
    J:339462 Valakh V, et al., A transcriptional constraint mechanism limits the homeostatic response to activity deprivation in mammalian neocortex. Elife. 2023 Feb 7;12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory