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Styx Gene Detail
Summary
  • Symbol
    Styx
  • Name
    serine/threonine/tyrosine interaction protein
  • Synonyms
    0610039A20Rik, STNS (alternatively spliced intron of Styx)
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891150
    NCBI Gene: 56291
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:45588534-45614608 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 22.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    529 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891150
 protein coding gene Chr14:45588534-45660277 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021208
 protein coding gene Chr14:38972566-39000365 (+)
A/J MGP_AJ_G0021154
 protein coding gene Chr14:37816295-37850712 (+)
AKR/J MGP_AKRJ_G0021132
 protein coding gene Chr14:39299591-39321951 (+)
BALB/cJ MGP_BALBcJ_G0021158
 protein coding gene Chr14:37866537-37889818 (+)
C3H/HeJ MGP_C3HHeJ_G0020941
 protein coding gene Chr14:39108150-39131033 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021592
 protein coding gene Chr14:40667247-40698098 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020907
 protein coding gene Chr14:41962137-41999512 (+)
DBA/2J MGP_DBA2J_G0021030
 protein coding gene Chr14:37738621-37760552 (+)
FVB/NJ MGP_FVBNJ_G0021014
 protein coding gene Chr14:37496364-37519421 (+)
LP/J MGP_LPJ_G0021100
 protein coding gene Chr14:39260073-39284640 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021040
 protein coding gene Chr14:41365171-41388185 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021625
 protein coding gene Chr14:38837871-38866342 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0020038
 protein coding gene Chr14:35006911-35032080 (+)
WSB/EiJ MGP_WSBEiJ_G0020522
 protein coding gene Chr14:38951579-38974651 (+)



Homology
more
  • Human Ortholog
    STYX, serine/threonine/tyrosine interacting protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STYX, serine/threonine/tyrosine interacting protein
  • Links
    NCBI Gene ID: 6815
    neXtProt AC: NX_Q8WUJ0
    UniProt: Q8WUJ0

  • Chr Location
    14q22.1; chr14:52730166-52774989 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males homozygous for a targeted null mutation are sterile due to a deficiency of germ cells at the immature, round, and elongating spermatid stages. Residual epididymal sperm have head abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56291 NCBI Gene Model | MGI Sequence Detail 26075 C57BL/6J ±  kb
    transcript NM_019637 RefSeq | MGI Sequence Detail 4258 C57BL/6  
    polypeptide Q60969 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:1918939
    References
    more
    • Summaries
      All 32
      Gene Ontology 6
      Phenotypes 8
    • Earliest
      J:20131 Kerr SM, et al., Analysis of cDNA sequences from mouse testis. Mamm Genome. 1994 Sep;5(9):557-65
    • Latest
      J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory