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Rpa2 Gene Detail
Summary
  • Symbol
    Rpa2
  • Name
    replication protein A2
  • Synonyms
    30-kDa protein, Rf-A2, RPA34
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339939
    NCBI Gene: 19891
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:132495671-132506057 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 65.88 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    409 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1339939
 protein coding gene Chr4:132495643-132506063 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028879
 protein coding gene Chr4:134955575-134966492 (+)
A/J MGP_AJ_G0028838
 protein coding gene Chr4:129333816-129344141 (+)
AKR/J MGP_AKRJ_G0028791
 protein coding gene Chr4:132979447-132991817 (+)
BALB/cJ MGP_BALBcJ_G0028861
 protein coding gene Chr4:129953164-129963489 (+)
C3H/HeJ MGP_C3HHeJ_G0028575
 protein coding gene Chr4:133239818-133251434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029303
 protein coding gene Chr4:139826291-139836998 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026574
 protein coding gene Chr4:122410215-122420702 (+)
CAST/EiJ MGP_CASTEiJ_G0028008
 protein coding gene Chr4:131308884-131321818 (+)
CBA/J MGP_CBAJ_G0028541
 protein coding gene Chr4:143401876-143416579 (+)
DBA/2J MGP_DBA2J_G0028690
 protein coding gene Chr4:129752712-129763357 (+)
FVB/NJ MGP_FVBNJ_G0028657
 protein coding gene Chr4:128615760-128626353 (+)
LP/J MGP_LPJ_G0028791
 protein coding gene Chr4:135100800-135113670 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028683
 protein coding gene Chr4:147996991-148008345 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029341
 protein coding gene Chr4:133398755-133410475 (+)
PWK/PhJ MGP_PWKPhJ_G0027729
 protein coding gene Chr4:126452720-126463307 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027555
 protein coding gene Chr4:129239991-129250008 (+)
WSB/EiJ MGP_WSBEiJ_G0028088
 protein coding gene Chr4:133566642-133579323 (+)



Homology
more
  • Human Ortholog
    RPA2, replication protein A2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPA2, replication protein A2
  • Synonyms
    REPA2, RPA32, RP-A p32, RP-A p34
  • Links
    NCBI Gene ID: 6118
    neXtProt AC: NX_P15927
    UniProt: P15927

  • Chr Location
    1p35.3; chr1:27891524-27914797 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    54
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    790
  • Tissues
    12
  • cDNA Data
    100
  • Literature Summary
    25
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19891 NCBI Gene Model | MGI Sequence Detail 10387 C57BL/6J ±  kb
transcript NM_011284 RefSeq | MGI Sequence Detail 1811 C57BL/6  
polypeptide Q62193 UniProt | EBI | MGI Sequence Detail 270 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 102
    cDNA 101
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140142, MGI:2140241, MGI:2140459
References
more
  • Summaries
    All 71
    Developmental Gene Expression 25
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:11379 Nakagawa M, et al., cDNA cloning of the murine 30-kDa protein homologous to the 32-kDa subunit of human replication protein A. Nucleic Acids Res. 1991 Aug 11;19(15):4292
  • Latest
    J:346053 Zhang J, et al., Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. Nat Commun. 2024 Mar 14;15(1):2315
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory