Tex261 MGI Mouse Gene Detail - MGI:1096575

Symbol

Tex261
Name

testis expressed gene 261
Synonyms

3110001O07Rik, TEG-261

Feature Type

protein coding gene
IDs

MGI:1096575
NCBI Gene: 21766
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr6:83745867-83752795 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 35.94 cM
Mapping Data

3 experiments

SNPs within 2kb

227 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1096575	protein coding gene	Chr6:83745863-83752804 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0030940	protein coding gene	Chr6:84803157-84811766 (-)
A/J	MGP_AJ_G0030909	protein coding gene	Chr6:81573654-81580956 (-)
AKR/J	MGP_AKRJ_G0030837	protein coding gene	Chr6:83934857-83941784 (-)
BALB/cJ	MGP_BALBcJ_G0030919	protein coding gene	Chr6:81601653-81608597 (-)
C3H/HeJ	MGP_C3HHeJ_G0030791	protein coding gene	Chr6:100466940-100473860 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0031379	protein coding gene	Chr6:87149316-87156265 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028565	protein coding gene	Chr6:79937415-79944359 (-)
CAST/EiJ	MGP_CASTEiJ_G0030028	protein coding gene	Chr6:83960832-83968711 (-)
CBA/J	MGP_CBAJ_G0030606	protein coding gene	Chr6:90567009-90576468 (-)
DBA/2J	MGP_DBA2J_G0030759	protein coding gene	Chr6:80886695-80893608 (-)
FVB/NJ	MGP_FVBNJ_G0030712	protein coding gene	Chr6:80098336-80106380 (-)
LP/J	MGP_LPJ_G0030838	protein coding gene	Chr6:84805005-84814275 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030748	protein coding gene	Chr6:94832800-94839749 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031403	protein coding gene	Chr6:83764487-83772824 (-)
PWK/PhJ	MGP_PWKPhJ_G0029743	protein coding gene	Chr6:79803870-79810865 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0029571	protein coding gene	Chr6:82587156-82594098 (-)
WSB/EiJ	MGP_WSBEiJ_G0030109	protein coding gene	Chr6:84181887-84189532 (-)

Human Ortholog

TEX261, testis expressed 261

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TEX261, testis expressed 261
Synonyms

TEG-261
Links

HGNC:30712

NCBI Gene ID: 113419

neXtProt AC: NX_Q6UWH6

UniProt: Q6UWH6
Chr Location

2p13.3; chr2:70968325-70994873 (-) GRCh38

MGI Vertebrate Homology

Tex261 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TEX261
Gene Tree

Tex261

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Phenotype Summary

17 phenotypes from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Endonuclease-mediated

1
Gene trapped

3
Spontaneous

1
Targeted

5
Genomic Mutations

2 involving Tex261
Incidental Mutations

APF
Find Mice (IMSR)

12 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

11
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

712
Tissues

1
cDNA Data

12
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tex261

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All Sequences

63
RefSeq

8
UniProt

2
CCDS

CCDS20285.1

Ensembl

ENSMUSG00000014748 (Evidence)
NCBI Gene

21766

			Length	Strain/Species	Flank
genomic	ENSMUSG00000014748	Ensembl Gene Model \| MGI Sequence Detail	6929	C57BL/6J	± kb
transcript	ENSMUST00000014892	Ensembl \| MGI Sequence Detail	2984	Not Applicable
polypeptide	ENSMUSP00000014892	Ensembl \| MGI Sequence Detail	196	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000016257 protein TEX261

(term hierarchy)
InterPro Domains

IPR007277 Svp26/Tex261
GlyGen

Q62302 1 site, 1 O-linked glycan (1 site)

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All nucleic 12

cDNA 12

Microarray probesets 6

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MGI:1889354, MGI:1915253, MGI:2141426, MGI:2141545

Summaries

All 40

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 14
Earliest

J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tex261:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr61711	Chr6:83752749-83752808 (-)	16 bp
Tssr61710	Chr6:83752728-83752741 (-)	60 bp
Tssr61709	Chr6:83752651-83752658 (-)	140 bp
Tssr61708	Chr6:83752592-83752597 (-)	200 bp
Tssr61707	Chr6:83752564-83752579 (-)	223 bp
Tssr61706	Chr6:83752557-83752562 (-)	235 bp
Tssr61705	Chr6:83752542-83752551 (-)	248 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24