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Cep170 Gene Detail
Summary
  • Symbol
    Cep170
  • Name
    centrosomal protein 170
  • Synonyms
    4933426L22Rik, A330004A13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918348
    NCBI Gene: 545389
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:176561219-176641633 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 82.60 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1295 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918348
 protein coding gene Chr1:176556638-176641633 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016845
 protein coding gene Chr1:182879771-182967499 (-)
A/J MGP_AJ_G0016824
 protein coding gene Chr1:175505772-175586679 (-)
AKR/J MGP_AKRJ_G0016790
 protein coding gene Chr1:180756268-180839819 (-)
BALB/cJ MGP_BALBcJ_G0016781
 protein coding gene Chr1:176033976-176114674 (-)
C3H/HeJ MGP_C3HHeJ_G0016607
 protein coding gene Chr1:181365254-181446952 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017246
 protein coding gene Chr1:188915489-189001169 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014952
 protein coding gene Chr1:166794692-166878880 (-)
CAST/EiJ MGP_CASTEiJ_G0016188
 protein coding gene Chr1:180724204-180818966 (-)
CBA/J MGP_CBAJ_G0016580
 protein coding gene Chr1:195794399-195888219 (-)
DBA/2J MGP_DBA2J_G0016686
 protein coding gene Chr1:174367808-174448832 (-)
FVB/NJ MGP_FVBNJ_G0016683
 protein coding gene Chr1:172456251-172539413 (-)
LP/J MGP_LPJ_G0016761
 protein coding gene Chr1:184070888-184154359 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016714
 protein coding gene Chr1:203018845-203113964 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017282
 protein coding gene Chr1:180494881-180575092 (-)
PWK/PhJ MGP_PWKPhJ_G0015975
 protein coding gene Chr1:173445705-173527123 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015752
 protein coding gene Chr1:179586731-179679418 (-)
WSB/EiJ MGP_WSBEiJ_G0016250
 protein coding gene Chr1:180717294-180806665 (-)



Homology
more
  • Human Ortholog
    CEP170, centrosomal protein 170
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEP170, centrosomal protein 170
  • Synonyms
    FAM68A, KAB, KIAA0470
  • Links
    NCBI Gene ID: 9859
    neXtProt AC: NX_Q5SW79
    UniProt: Q5SW79

  • Chr Location
    1q43; chr1:243124428-243255793 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    75
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057335 Ensembl Gene Model | MGI Sequence Detail 80415 C57BL/6J ±  kb
transcript ENSMUST00000194727 Ensembl | MGI Sequence Detail 6784 Not Applicable  
polypeptide ENSMUSP00000141793 Ensembl | MGI Sequence Detail 1588 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000005344 centrosomal protein of 170 kDa
    (term hierarchy)
  • InterPro Domains
    IPR051176 Centrosomal and Immune Signaling Modulators
    IPR029300 CEP170, C-terminal
    IPR000253 Forkhead-associated (FHA) domain
    IPR008984 SMAD/FHA domain superfamily
  • GlyGen
    Q6A065 6 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (5 sites)
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138171, MGI:2444094
References
more
  • Summaries
    All 44
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:305154 Wilkinson B, et al., Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders. Biol Psychiatry. 2019 Feb 15;85(4):305-316
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory