About   Help   FAQ
Zfp646 Gene Detail
Summary
  • Symbol
    Zfp646
  • Name
    zinc finger protein 646
  • Feature Type
    protein coding gene
  • IDs
    MGI:3665412
    NCBI Gene: 233905
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:127476081-127485168 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    230 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3665412
 protein coding gene Chr7:127475393-127485168 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033059
 protein coding gene Chr7:132259423-132269198 (+)
A/J MGP_AJ_G0033042
 protein coding gene Chr7:128720389-128730164 (+)
AKR/J MGP_AKRJ_G0032974
 protein coding gene Chr7:132049172-132058947 (+)
BALB/cJ MGP_BALBcJ_G0033043
 protein coding gene Chr7:128373365-128383140 (+)
C3H/HeJ MGP_C3HHeJ_G0032757
 protein coding gene Chr7:131951536-131962440 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033552
 protein coding gene Chr7:137407751-137417526 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030525
 protein coding gene Chr7:129911253-129921177 (+)
CAST/EiJ MGP_CASTEiJ_G0032086
 protein coding gene Chr7:123745509-123755288 (+)
CBA/J MGP_CBAJ_G0032730
 protein coding gene Chr7:142078216-142087991 (+)
DBA/2J MGP_DBA2J_G0032882
 protein coding gene Chr7:126697419-126707194 (+)
FVB/NJ MGP_FVBNJ_G0032835
 protein coding gene Chr7:126557486-126567261 (+)
LP/J MGP_LPJ_G0032976
 protein coding gene Chr7:133730653-133740428 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032867
 protein coding gene Chr7:143148110-143157885 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033572
 protein coding gene Chr7:131039171-131048946 (+)
PWK/PhJ MGP_PWKPhJ_G0031793
 protein coding gene Chr7:119705379-119715164 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031639
 protein coding gene Chr7:117850549-117860307 (+)
WSB/EiJ MGP_WSBEiJ_G0032198
 protein coding gene Chr7:132005320-132015095 (+)



Homology
more
  • Human Ortholog
    ZNF646, zinc finger protein 646
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF646, zinc finger protein 646
  • Links
    NCBI Gene ID: 9726
    neXtProt AC: NX_O15015
    UniProt: O15015

  • Chr Location
    16p11.2; chr16:31072687-31084196 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    23
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 233905 NCBI Gene Model | MGI Sequence Detail 9088 C57BL/6J ±  kb
transcript NM_001404059 RefSeq | MGI Sequence Detail 6412 C57BL/6  
polypeptide Q6NV66 UniProt | EBI | MGI Sequence Detail 1788 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory