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Lpcat4 Gene Detail
Summary
  • Symbol
    Lpcat4
  • Name
    lysophosphatidylcholine acyltransferase 4
  • Synonyms
    Agpat7, Aytl3, LPEAT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138993
    NCBI Gene: 99010
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:112070186-112077456 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 56.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    213 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138993
 protein coding gene Chr2:112069813-112077456 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026284
 protein coding gene Chr2:114682535-114690183 (+)
A/J MGP_AJ_G0026245
 protein coding gene Chr2:109983791-109991617 (+)
AKR/J MGP_AKRJ_G0026224
 protein coding gene Chr2:113070961-113079000 (+)
BALB/cJ MGP_BALBcJ_G0026258
 protein coding gene Chr2:110251344-110258995 (+)
C3H/HeJ MGP_C3HHeJ_G0026003
 protein coding gene Chr2:113463186-113474749 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026705
 protein coding gene Chr2:118485252-118492880 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024085
 protein coding gene Chr2:105216657-105224302 (+)
CAST/EiJ MGP_CASTEiJ_G0025467
 protein coding gene Chr2:113738522-113749494 (+)
CBA/J MGP_CBAJ_G0025980
 protein coding gene Chr2:122615632-122625170 (+)
DBA/2J MGP_DBA2J_G0026119
 protein coding gene Chr2:109439978-109447623 (+)
FVB/NJ MGP_FVBNJ_G0026081
 protein coding gene Chr2:108327687-108335318 (+)
LP/J MGP_LPJ_G0026220
 protein coding gene Chr2:114963315-114971758 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026100
 protein coding gene Chr2:127014381-127027397 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026760
 protein coding gene Chr2:113141486-113149123 (+)
PWK/PhJ MGP_PWKPhJ_G0025202
 protein coding gene Chr2:108947692-108955417 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025001
 protein coding gene Chr2:112329965-112337632 (+)
WSB/EiJ MGP_WSBEiJ_G0025535
 protein coding gene Chr2:113949099-113956691 (+)



Homology
more
  • Human Ortholog
    LPCAT4, lysophosphatidylcholine acyltransferase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LPCAT4, lysophosphatidylcholine acyltransferase 4
  • Synonyms
    AGPAT7, AYTL3, LPAAT-eta, LPEAT2, LPLAT10
  • Links
    NCBI Gene ID: 254531
    neXtProt AC: NX_Q643R3
    UniProt: Q643R3

  • Chr Location
    15q14; chr15:34358633-34367196 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    801
  • Tissues
    95
  • cDNA Data
    17
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 99010 NCBI Gene Model | MGI Sequence Detail 7271 C57BL/6J ±  kb
transcript NM_207206 RefSeq | MGI Sequence Detail 1920 C57BL/6  
polypeptide Q6NVG1 UniProt | EBI | MGI Sequence Detail 524 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:298548 Eto M, et al., Lysophosphatidylethanolamine acyltransferase 2 (LPEAT2) incorporates DHA into phospholipids and has possible functions for fatty acid-induced cell death. Biochem Biophys Res Commun. 2020 May 21;526(1):246-252
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory