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Fbxo42 Gene Detail
Summary
  • Symbol
    Fbxo42
  • Name
    F-box protein 42
  • Synonyms
    6720460I06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924992
    NCBI Gene: 213499
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:140875224-140931373 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 73.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1575 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924992
 protein coding gene Chr4:140875216-140931373 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029040
 protein coding gene Chr4:144164714-144235464 (+)
A/J MGP_AJ_G0028999
 protein coding gene Chr4:137913051-137971454 (+)
AKR/J MGP_AKRJ_G0028951
 protein coding gene Chr4:141890382-141948012 (+)
BALB/cJ MGP_BALBcJ_G0029023
 protein coding gene Chr4:138601007-138664538 (+)
C3H/HeJ MGP_C3HHeJ_G0028737
 protein coding gene Chr4:142266825-142325591 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029464
 protein coding gene Chr4:149217612-149278095 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026735
 protein coding gene Chr4:130826876-130883847 (+)
CAST/EiJ MGP_CASTEiJ_G0028169
 protein coding gene Chr4:140523139-140581945 (+)
CBA/J MGP_CBAJ_G0028701
 protein coding gene Chr4:153520550-153584997 (+)
DBA/2J MGP_DBA2J_G0028851
 protein coding gene Chr4:138304206-138364732 (+)
FVB/NJ MGP_FVBNJ_G0028818
 protein coding gene Chr4:137409623-137470188 (+)
LP/J MGP_LPJ_G0028950
 protein coding gene Chr4:144186290-144246407 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028844
 protein coding gene Chr4:157365244-157426082 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029502
 protein coding gene Chr4:142418511-142476596 (+)
PWK/PhJ MGP_PWKPhJ_G0027890
 protein coding gene Chr4:135192683-135250983 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027715
 protein coding gene Chr4:138234035-138296030 (+)
WSB/EiJ MGP_WSBEiJ_G0028247
 protein coding gene Chr4:142698755-142757842 (+)



Homology
more
  • Human Ortholog
    FBXO42, F-box protein 42
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO42, F-box protein 42
  • Synonyms
    Fbx42, JFK
  • Links
    NCBI Gene ID: 54455
    neXtProt AC: NX_Q6P3S6
    UniProt: Q6P3S6

  • Chr Location
    1p36.13; chr1:16246840-16352480 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    5
  • cDNA Data
    105
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028920 Ensembl Gene Model | MGI Sequence Detail 56150 C57BL/6J ±  kb
    transcript ENSMUST00000030757 Ensembl | MGI Sequence Detail 5934 Not Applicable  
    polypeptide ENSMUSP00000030757 Ensembl | MGI Sequence Detail 717 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 105
      cDNA 105

      Microarray probesets 3
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory