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Dhx29 Gene Detail
Summary
  • Symbol
    Dhx29
  • Name
    DExH-box helicase 29
  • Synonyms
    DEAH (Asp-Glu-Ala-His) box polypeptide 29, E130202M19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145374
    NCBI Gene: 218629
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:113063988-113105966 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 63.93 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1680 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145374
 protein coding gene Chr13:113063976-113105968 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020942
 protein coding gene Chr13:115520527-115569659 (+)
A/J MGP_AJ_G0020892
 protein coding gene Chr13:110909301-110951410 (+)
AKR/J MGP_AKRJ_G0020867
 protein coding gene Chr13:114256661-114298044 (+)
BALB/cJ MGP_BALBcJ_G0020892
 protein coding gene Chr13:111600643-111642601 (+)
C3H/HeJ MGP_C3HHeJ_G0020681
 protein coding gene Chr13:114049970-114092341 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021328
 protein coding gene Chr13:118943683-118985013 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018897
 protein coding gene Chr13:106196324-106239709 (+)
CAST/EiJ MGP_CASTEiJ_G0020201
 protein coding gene Chr13:113674748-113726449 (+)
CBA/J MGP_CBAJ_G0020643
 protein coding gene Chr13:123546084-123590249 (+)
DBA/2J MGP_DBA2J_G0020766
 protein coding gene Chr13:110618861-110660680 (+)
FVB/NJ MGP_FVBNJ_G0020750
 protein coding gene Chr13:109313997-109356749 (+)
LP/J MGP_LPJ_G0020842
 protein coding gene Chr13:115561413-115603358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020778
 protein coding gene Chr13:123799158-123847007 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021364
 protein coding gene Chr13:113720342-113763449 (+)
PWK/PhJ MGP_PWKPhJ_G0019954
 protein coding gene Chr13:109367698-109409995 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019776
 protein coding gene Chr13:110029338-110076375 (+)
WSB/EiJ MGP_WSBEiJ_G0020258
 protein coding gene Chr13:114313115-114356576 (+)



Homology
more
  • Human Ortholog
    DHX29, DExH-box helicase 29
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DHX29, DExH-box helicase 29
  • Synonyms
    DDX29
  • Links
    NCBI Gene ID: 54505
    neXtProt AC: NX_Q7Z478
    UniProt: Q7Z478

  • Chr Location
    5q11.2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    46
  • cDNA Data
    17
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042426 Ensembl Gene Model | MGI Sequence Detail 41979 C57BL/6J ±  kb
    transcript ENSMUST00000038574 Ensembl | MGI Sequence Detail 4682 Not Applicable  
    polypeptide ENSMUSP00000035244 Ensembl | MGI Sequence Detail 1365 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000006471 ATP-dependent RNA helicase DHX29
      (term hierarchy)
    • EC
      3.6.4.13
    • InterPro Domains
      IPR034730 ATP-dependent RNA helicase DHX29
      IPR011709 DEAD-box helicase, OB fold
      IPR011545 DEAD/DEAH box helicase domain
      IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
      IPR007502 Helicase-associated domain
      IPR048333 Helicase associated domain (HA2), winged-helix domain
      IPR001650 Helicase, C-terminal domain-like
      IPR014001 Helicase superfamily 1/2, ATP-binding domain
      IPR027417 P-loop containing nucleoside triphosphate hydrolase
    • GlyGen
      Q6PGC1 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1926111
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 10
      Phenotypes 12
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory