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Ptx4 Gene Detail
Summary
  • Symbol
    Ptx4
  • Name
    pentraxin 4
  • Synonyms
    1110018H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915759
    NCBI Gene: 68509
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:25339734-25344266 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.53 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    239 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915759
 protein coding gene Chr17:25339328-25344266 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023339
 protein coding gene Chr17:24159445-24163953 (+)
A/J MGP_AJ_G0023298
 protein coding gene Chr17:23489376-23493882 (+)
AKR/J MGP_AKRJ_G0023264
 protein coding gene Chr17:23580265-23584773 (+)
BALB/cJ MGP_BALBcJ_G0023303
 protein coding gene Chr17:23683951-23688459 (+)
C3H/HeJ MGP_C3HHeJ_G0023063
 protein coding gene Chr17:23950143-23954651 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023746
 protein coding gene Chr17:25221112-25225620 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021221
 protein coding gene Chr17:20945406-20950185 (+)
CAST/EiJ MGP_CASTEiJ_G0022565
 protein coding gene Chr17:23797190-23801670 (+)
CBA/J MGP_CBAJ_G0023038
 protein coding gene Chr17:26081255-26085763 (+)
DBA/2J MGP_DBA2J_G0023168
 protein coding gene Chr17:23077965-23082475 (+)
FVB/NJ MGP_FVBNJ_G0023138
 protein coding gene Chr17:22798340-22802850 (+)
LP/J MGP_LPJ_G0023245
 protein coding gene Chr17:24457346-24461854 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023157
 protein coding gene Chr17:25748254-25752770 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023785
 protein coding gene Chr17:23862052-23866568 (+)
PWK/PhJ MGP_PWKPhJ_G0022314
 protein coding gene Chr17:21835497-21840069 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022132
 protein coding gene Chr17:21925175-21929681 (+)
WSB/EiJ MGP_WSBEiJ_G0022628
 protein coding gene Chr17:23932932-23937432 (+)



Homology
more
  • Human Ortholog
    PTX4, pentraxin 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTX4, pentraxin 4
  • Synonyms
    C16orf38
  • Links
    NCBI Gene ID: 390667
    neXtProt AC: NX_Q96A99
    UniProt: Q96A99

  • Chr Location
    16p13.3; chr16:1485886-1488981 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044172 Ensembl Gene Model | MGI Sequence Detail 4533 C57BL/6J ±  kb
transcript ENSMUST00000054930 Ensembl | MGI Sequence Detail 1582 Not Applicable  
polypeptide ENSMUSP00000055984 Ensembl | MGI Sequence Detail 482 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory