Paqr6 MGI Mouse Gene Detail - MGI:1916207 - progestin and adipoQ receptor family member VI

Symbol

Paqr6
Name

progestin and adipoQ receptor family member VI
Synonyms

1500001B10Rik

Feature Type

protein coding gene
IDs

MGI:1916207
NCBI Gene: 68957
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr3:88271891-88275848 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 38.81 cM
Mapping Data

1 experiment

SNPs within 2kb

202 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916207	protein coding gene	Chr3:88271376-88275848 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027392	protein coding gene	Chr3:88519595-88539289 (+)
A/J	MGP_AJ_G0027356	protein coding gene	Chr3:85521327-85551900 (+)
AKR/J	MGP_AKRJ_G0027322	protein coding gene	Chr3:87625933-87649310 (+)
BALB/cJ	MGP_BALBcJ_G0027365	protein coding gene	Chr3:85611591-85628229 (+)
C3H/HeJ	MGP_C3HHeJ_G0027108	protein coding gene	Chr3:87902117-87910506 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027811	protein coding gene	Chr3:91778690-91786208 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025164	protein coding gene	Chr3:81141199-81145297 (+)
CAST/EiJ	MGP_CASTEiJ_G0026554	protein coding gene	Chr3:88117876-88151817 (+)
CBA/J	MGP_CBAJ_G0027083	protein coding gene	Chr3:94900363-94903357 (+)
DBA/2J	MGP_DBA2J_G0027219	protein coding gene	Chr3:85010637-85019885 (+)
FVB/NJ	MGP_FVBNJ_G0027188	protein coding gene	Chr3:83281345-83287248 (+)
LP/J	MGP_LPJ_G0027327	protein coding gene	Chr3:89514163-89540897 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027207	protein coding gene	Chr3:101136668-101152573 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027869	protein coding gene	Chr3:87381979-87389334 (+)
PWK/PhJ	MGP_PWKPhJ_G0026287	protein coding gene	Chr3:84809589-84813579 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026105	protein coding gene	Chr3:86572380-86576391 (+)
WSB/EiJ	MGP_WSBEiJ_G0026634	protein coding gene	Chr3:87734618-87754453 (+)

Human Ortholog

PAQR6, progestin and adipoQ receptor family member 6

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PAQR6, progestin and adipoQ receptor family member 6
Synonyms

PRdelta
Links

HGNC:30132

NCBI Gene ID: 79957

neXtProt AC: NX_Q6TCH4

UniProt: Q6TCH4
Chr Location

1q22; chr1:156243320-156248117 (-) GRCh38

MGI Vertebrate Homology

Paqr6 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: PAQR6
Gene Tree

Paqr6

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References

1 with disease annotations

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

1
Gene trapped

1
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Paqr6
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

13 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

3
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

797
Tissues

13
cDNA Data

16
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase paqr6

ZFIN paqr6

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All Sequences

55
RefSeq

14
UniProt

3
CCDS

CCDS17471.1, CCDS79941.1

Ensembl

ENSMUSG00000041423 (Evidence)
NCBI Gene

68957

			Length	Strain/Species	Flank
genomic	ENSMUSG00000041423	Ensembl Gene Model \| MGI Sequence Detail	3958	C57BL/6J	± kb
transcript	ENSMUST00000147991	Ensembl \| MGI Sequence Detail	1670	Not Applicable
polypeptide	ENSMUSP00000114166	Ensembl \| MGI Sequence Detail	343	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000030423 membrane progestin receptor delta

(term hierarchy)
InterPro Domains

IPR004254 AdipoR/Haemolysin-III-related

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All nucleic 16

cDNA 16

Microarray probesets 3

Summaries

All 34

Developmental Gene Expression 1

Diseases 1

Gene Ontology 3

Phenotypes 13
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Paqr6:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr29947	Chr3:88271855-88271913 (+)	-7 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24