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Tmsb10 Gene Detail
Summary
  • Symbol
    Tmsb10
  • Name
    thymosin beta 10
  • Synonyms
    Ptmb10, Tb10
  • Feature Type
    protein coding gene
  • IDs
    MGI:109146
    NCBI Gene: 19240
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:72934330-72935731 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.35 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109146
 protein coding gene Chr6:72934330-72935731 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030885
 protein coding gene Chr6:73571218-73572619 (-)
A/J MGP_AJ_G0030855
 protein coding gene Chr6:70657721-70659122 (-)
AKR/J MGP_AKRJ_G0030784
 protein coding gene Chr6:72788152-72789559 (-)
BALB/cJ MGP_BALBcJ_G0030866
 protein coding gene Chr6:70718050-70719457 (-)
C3H/HeJ MGP_C3HHeJ_G0030846
 protein coding gene Chr6:111463632-111464376 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031324
 protein coding gene Chr6:75479124-75480623 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028513
 protein coding gene Chr6:69826751-69828162 (-)
CAST/EiJ MGP_CASTEiJ_G0029974
 protein coding gene Chr6:72655836-72656587 (-)
CBA/J MGP_CBAJ_G0030553
 protein coding gene Chr6:78582429-78583173 (-)
DBA/2J MGP_DBA2J_G0030705
 protein coding gene Chr6:70079990-70082340 (-)
FVB/NJ MGP_FVBNJ_G0030658
 protein coding gene Chr6:69477781-69478525 (-)
LP/J MGP_LPJ_G0030784
 protein coding gene Chr6:73468166-73468910 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030693
 protein coding gene Chr6:81927636-81929038 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031350
 protein coding gene Chr6:72610487-72611231 (-)
PWK/PhJ MGP_PWKPhJ_G0029690
 protein coding gene Chr6:69008790-69009530 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029518
 protein coding gene Chr6:71358420-71359927 (-)
WSB/EiJ MGP_WSBEiJ_G0030056
 protein coding gene Chr6:72990741-72991492 (-)



Homology
more
  • Human Ortholog
    TMSB10, thymosin beta 10
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMSB10, thymosin beta 10
  • Synonyms
    MIG12, TB10
  • Links
    NCBI Gene ID: 9168
    neXtProt AC: NX_P63313
    UniProt: P63313

  • Chr Location
    2p11.2; chr2:84905656-84906671 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    838
  • Tissues
    116
  • cDNA Data
    27
  • Literature Summary
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19240 NCBI Gene Model | MGI Sequence Detail 1402 C57BL/6J ±  kb
transcript NM_001190327 RefSeq | MGI Sequence Detail 637 C57BL/6  
polypeptide Q6ZWY8 UniProt | EBI | MGI Sequence Detail 44 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • GlyGen
    Q6ZWY8 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 36
    cDNA 30
    Primer pair 3
    Other 3

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-38190
References
more
  • Summaries
    All 52
    Developmental Gene Expression 15
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:36377 Carpintero P, et al., Thymosin beta10 mRNA expression during early postimplantation mouse development. FEBS Lett. 1996 Sep 23;394(1):103-6
  • Latest
    J:325730 Ahuja N, et al., Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory