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Msrb2 Gene Detail
Summary
  • Symbol
    Msrb2
  • Name
    methionine sulfoxide reductase B2
  • Synonyms
    2310050L06Rik, Msrb
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923717
    NCBI Gene: 76467
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:19376251-19399787 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 13.26 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    901 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923717
 protein coding gene Chr2:19376247-19399787 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025381
 protein coding gene Chr2:17101925-17133183 (+)
A/J MGP_AJ_G0025359
 protein coding gene Chr2:16387283-16420664 (+)
AKR/J MGP_AKRJ_G0025327
 protein coding gene Chr2:16974267-16998306 (+)
BALB/cJ MGP_BALBcJ_G0025354
 protein coding gene Chr2:16460478-16483484 (+)
C3H/HeJ MGP_C3HHeJ_G0025114
 protein coding gene Chr2:16877958-16904270 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025797
 protein coding gene Chr2:17573446-17598450 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023212
 protein coding gene Chr2:15780812-15804687 (+)
CAST/EiJ MGP_CASTEiJ_G0024578
 protein coding gene Chr2:16827762-16853059 (+)
CBA/J MGP_CBAJ_G0025093
 protein coding gene Chr2:18324876-18353620 (+)
DBA/2J MGP_DBA2J_G0025225
 protein coding gene Chr2:16344801-16368152 (+)
FVB/NJ MGP_FVBNJ_G0025188
 protein coding gene Chr2:16149423-16173345 (+)
LP/J MGP_LPJ_G0025312
 protein coding gene Chr2:16925657-16951874 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025219
 protein coding gene Chr2:18276438-18302472 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025855
 protein coding gene Chr2:16906628-16933975 (+)
PWK/PhJ MGP_PWKPhJ_G0024327
 protein coding gene Chr2:16218560-16242985 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024127
 protein coding gene Chr2:17035303-17065597 (+)
WSB/EiJ MGP_WSBEiJ_G0024648
 protein coding gene Chr2:16985707-17011329 (+)



Homology
more
  • Human Ortholog
    MSRB2, methionine sulfoxide reductase B2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MSRB2, methionine sulfoxide reductase B2
  • Synonyms
    CBS-1, CBS1, CGI-131, MSRB, PILB
  • Links
    NCBI Gene ID: 22921
    neXtProt AC: NX_Q9Y3D2
    UniProt: Q9Y3D2

  • Chr Location
    10p12.2; chr10:23095579-23122013 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    8
  • cDNA Data
    30
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023094 Ensembl Gene Model | MGI Sequence Detail 23537 C57BL/6J ±  kb
transcript ENSMUST00000023856 Ensembl | MGI Sequence Detail 1196 Not Applicable  
polypeptide ENSMUSP00000023856 Ensembl | MGI Sequence Detail 175 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 30
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:294426 Lee SH, et al., Mitochondrial MsrB2 serves as a switch and transducer for mitophagy. EMBO Mol Med. 2019 Aug;11(8):e10409
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory