Rsbn1 MGI Mouse Gene Detail - MGI:2444993 - rosbin, round spermatid basic protein 1

Symbol

Rsbn1
Name

rosbin, round spermatid basic protein 1
Synonyms

C230004D03Rik, mKIAA3002, Rsbp

Feature Type

protein coding gene
IDs

MGI:2444993
NCBI Gene: 229675
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr3:103821436-103873952 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 45.52 cM
Mapping Data

1 experiment

SNPs within 2kb

161 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444993	protein coding gene	Chr3:103821412-103873952 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027703	protein coding gene	Chr3:105213634-105271193 (+)
A/J	MGP_AJ_G0027663	protein coding gene	Chr3:101863660-101914971 (+)
AKR/J	MGP_AKRJ_G0027628	protein coding gene	Chr3:104345826-104401143 (+)
BALB/cJ	MGP_BALBcJ_G0027675	protein coding gene	Chr3:101630631-101683687 (+)
C3H/HeJ	MGP_C3HHeJ_G0027405	protein coding gene	Chr3:104716812-104775078 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028119	protein coding gene	Chr3:109105923-109166910 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025459	protein coding gene	Chr3:97985673-98040188 (+)
CAST/EiJ	MGP_CASTEiJ_G0026861	protein coding gene	Chr3:103833146-103886625 (+)
CBA/J	MGP_CBAJ_G0027380	protein coding gene	Chr3:112845506-112900047 (+)
DBA/2J	MGP_DBA2J_G0027522	protein coding gene	Chr3:101106973-101159044 (+)
FVB/NJ	MGP_FVBNJ_G0027490	protein coding gene	Chr3:99032383-99085367 (+)
LP/J	MGP_LPJ_G0027629	protein coding gene	Chr3:106555874-106607863 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027520	protein coding gene	Chr3:118969555-119023092 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028174	protein coding gene	Chr3:103902691-103959265 (+)
PWK/PhJ	MGP_PWKPhJ_G0026587	protein coding gene	Chr3:100882798-100935984 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026408	protein coding gene	Chr3:101969676-102022414 (+)
WSB/EiJ	MGP_WSBEiJ_G0026941	protein coding gene	Chr3:104459694-104516501 (+)

Human Ortholog

RSBN1, round spermatid basic protein 1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RSBN1, round spermatid basic protein 1
Synonyms

KDM9, ROSBIN
Links

HGNC:25642

NCBI Gene ID: 54665

neXtProt AC: NX_Q5VWQ0

UniProt: Q5VWQ0
Chr Location

1p13.2; chr1:113761832-113812476 (-) GRCh38

MGI Vertebrate Homology

Rsbn1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: RSBN1
Gene Tree

Rsbn1

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References

1 with disease annotations

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Phenotype Summary

7 phenotypes from 1 allele in 1 genetic background
17 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

13
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

4
Radiation induced

1
Targeted

6
Genomic Mutations

2 involving Rsbn1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

47 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

710
Tissues

4
cDNA Data

10
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rsbn1

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All Sequences

58
RefSeq

11
UniProt

3
CCDS

CCDS17697.1

Ensembl

ENSMUSG00000044098 (Evidence)
NCBI Gene

229675

			Length	Strain/Species	Flank
genomic	ENSMUSG00000044098	Ensembl Gene Model \| MGI Sequence Detail	52517	C57BL/6J	± kb
transcript	ENSMUST00000051139	Ensembl \| MGI Sequence Detail	4762	Not Applicable
polypeptide	ENSMUSP00000058934	Ensembl \| MGI Sequence Detail	795	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000014319 lysine-specific demethylase 9

(term hierarchy)
EC

1.14.11.-
InterPro Domains

IPR039775 Homeodomain containing protein PHTF1/2

IPR026306 RSBN1/Dpy-21

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All nucleic 10

cDNA 10

Microarray probesets 6

Summaries

All 40

Developmental Gene Expression 1

Diseases 1

Gene Ontology 5

Phenotypes 17
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Rsbn1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr31033	Chr3:103821415-103821434 (+)	-11 bp
Tssr993	Chr3:103821558-103821560 (+)	123 bp
Tssr31034	Chr3:103821687-103821721 (+)	268 bp
Tssr31035	Chr3:103821728-103821746 (+)	301 bp
Tssr31036	Chr3:103821876-103821921 (+)	463 bp
Tssr31037	Chr3:103821929-103821940 (+)	499 bp
Tssr31038	Chr3:103826942-103826946 (+)	5,508 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24