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Fads6 Gene Detail
Summary
  • Symbol
    Fads6
  • Name
    fatty acid desaturase domain family, member 6
  • Synonyms
    BC050213, OTTMUSG00000021749
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039592
    NCBI Gene: 328035
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115170448-115188489 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    554 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3039592
protein coding gene Chr11:115169453-115188489 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019378
protein coding gene Chr11:119288377-119310595 (-)
A/J MGP_AJ_G0019347
protein coding gene Chr11:114081994-114100418 (-)
AKR/J MGP_AKRJ_G0019317
protein coding gene Chr11:117482200-117505654 (-)
BALB/cJ MGP_BALBcJ_G0019321
protein coding gene Chr11:114498703-114517027 (-)
C3H/HeJ MGP_C3HHeJ_G0019127
protein coding gene Chr11:117836260-117856002 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019771
protein coding gene Chr11:122928859-122951016 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017394
protein coding gene Chr11:111123609-111141411 (-)
CAST/EiJ MGP_CASTEiJ_G0018682
protein coding gene Chr11:119148603-119169919 (-)
CBA/J MGP_CBAJ_G0019099
protein coding gene Chr11:127775960-127794047 (-)
DBA/2J MGP_DBA2J_G0019210
protein coding gene Chr11:113521152-113539306 (-)
FVB/NJ MGP_FVBNJ_G0019202
protein coding gene Chr11:112992577-113012523 (-)
LP/J MGP_LPJ_G0019280
protein coding gene Chr11:119672053-119695240 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019235
protein coding gene Chr11:126956499-126975537 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019809
protein coding gene Chr11:118145120-118164940 (-)
PWK/PhJ MGP_PWKPhJ_G0018446
protein coding gene Chr11:114798431-114816681 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018239
protein coding gene Chr11:117886581-117906424 (-)
WSB/EiJ MGP_WSBEiJ_G0018734
protein coding gene Chr11:118089574-118108741 (-)



Homology
more
  • Human Ortholog
    FADS6, fatty acid desaturase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FADS6, fatty acid desaturase 6
  • Synonyms
    FP18279
  • Links
    NCBI Gene ID: 283985
    neXtProt AC: NX_Q8N9I5
    UniProt: Q8N9I5

  • Chr Location
    17q25.1; chr17:74874787-74893781 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000044788 Ensembl Gene Model | MGI Sequence Detail 18042 C57BL/6J ±  kb
    transcript ENSMUST00000056153 Ensembl | MGI Sequence Detail 4951 Not Applicable  
    polypeptide ENSMUSP00000058783 Ensembl | MGI Sequence Detail 342 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 21

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3707356
    References
    more
    • Summaries
      All 35
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:82022 Kikkawa Y, et al., Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice. Hum Mol Genet. 2003 Mar 1;12(5):453-61
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    10/22/2024
    MGI 6.24
    The Jackson Laboratory