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Atg2b Gene Detail
Summary
  • Symbol
    Atg2b
  • Name
    autophagy related 2B
  • Synonyms
    2410024A21Rik, C030004M05Rik, C630028L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923809
    NCBI Gene: 76559
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:105582395-105651470 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 55.82 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1718 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923809
protein coding gene Chr12:105579798-105651554 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020093
protein coding gene Chr12:107494626-107565556 (-)
A/J MGP_AJ_G0020047
protein coding gene Chr12:103479416-103551735 (-)
AKR/J MGP_AKRJ_G0020023
protein coding gene Chr12:106482663-106555433 (-)
BALB/cJ MGP_BALBcJ_G0020033
protein coding gene Chr12:103897434-103968640 (-)
C3H/HeJ MGP_C3HHeJ_G0019835
protein coding gene Chr12:106912032-106982631 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020478
protein coding gene Chr12:110806402-110879410 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018090
protein coding gene Chr12:100089622-100156353 (-)
CAST/EiJ MGP_CASTEiJ_G0019377
protein coding gene Chr12:101715565-101788917 (-)
CBA/J MGP_CBAJ_G0019802
protein coding gene Chr12:115196152-115270635 (-)
DBA/2J MGP_DBA2J_G0019919
protein coding gene Chr12:103005506-103076006 (-)
FVB/NJ MGP_FVBNJ_G0019904
protein coding gene Chr12:101794654-101862303 (-)
LP/J MGP_LPJ_G0019994
protein coding gene Chr12:107392726-107463651 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019942
protein coding gene Chr12:118599974-118678393 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020507
protein coding gene Chr12:105864593-105943635 (-)
PWK/PhJ MGP_PWKPhJ_G0019136
protein coding gene Chr12:97598680-97666434 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018940
protein coding gene Chr12:100099401-100166946 (-)
WSB/EiJ MGP_WSBEiJ_G0019434
protein coding gene Chr12:106828556-106898353 (-)



Homology
more
  • Human Ortholog
    ATG2B, autophagy related 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATG2B, autophagy related 2B
  • Synonyms
    BLTP4B, C14orf103
  • Links
    NCBI Gene ID: 55102
    neXtProt AC: NX_Q96BY7
    UniProt: Q96BY7

  • Chr Location
    14q32.2; chr14:96279195-96363341 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041341 Ensembl Gene Model | MGI Sequence Detail 69076 C57BL/6J ±  kb
    transcript ENSMUST00000041055 Ensembl | MGI Sequence Detail 7546 Not Applicable  
    polypeptide ENSMUSP00000037441 Ensembl | MGI Sequence Detail 2075 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000004412 autophagy-related protein 2 homolog B
    • InterPro Domains
      IPR015412 Atg2/VPS13, C-terminal
      IPR026849 Autophagy-related protein 2
      IPR026885 Autophagy-related protein 2, middle RBG module
      IPR026854 Vacuolar protein sorting-associated protein 13-like, N-terminal domain
    Molecular
    Reagents
    less
    • All nucleic 18
      Genomic 2
      cDNA 16

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1926114, MGI:2144758, MGI:2144850, MGI:2145049, MGI:2441919
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 8
    • Earliest
      J:34253 Gaubatz JW, et al., Mouse satellite DNA is transcribed in senescent cardiac muscle. J Biol Chem. 1990 Oct 15;265(29):17753-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/19/2024
    MGI 6.24
    The Jackson Laboratory