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Them6 Gene Detail
Summary
  • Symbol
    Them6
  • Name
    thioesterase superfamily member 6
  • Synonyms
    4930572J05Rik, MGC:54796
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925301
    NCBI Gene: 223626
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:74593083-74596222 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.26 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    162 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925301
 protein coding gene Chr15:74593053-74596488 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021932
 protein coding gene Chr15:74503665-74507097 (+)
A/J MGP_AJ_G0021891
 protein coding gene Chr15:71845095-71848530 (+)
AKR/J MGP_AKRJ_G0021873
 protein coding gene Chr15:73685672-73689108 (+)
BALB/cJ MGP_BALBcJ_G0021898
 protein coding gene Chr15:71852415-71856125 (+)
C3H/HeJ MGP_C3HHeJ_G0021671
 protein coding gene Chr15:73838721-73842171 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022338
 protein coding gene Chr15:77317586-77324365 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019874
 protein coding gene Chr15:68257186-68260654 (+)
CAST/EiJ MGP_CASTEiJ_G0021190
 protein coding gene Chr15:74659849-74663284 (+)
CBA/J MGP_CBAJ_G0021637
 protein coding gene Chr15:79853432-79857008 (+)
DBA/2J MGP_DBA2J_G0021762
 protein coding gene Chr15:71443397-71446880 (+)
FVB/NJ MGP_FVBNJ_G0021744
 protein coding gene Chr15:70486130-70489822 (+)
LP/J MGP_LPJ_G0021834
 protein coding gene Chr15:74562990-74566399 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021767
 protein coding gene Chr15:85169143-85172557 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022359
 protein coding gene Chr15:74073545-74077032 (+)
PWK/PhJ MGP_PWKPhJ_G0020931
 protein coding gene Chr15:71549114-71552590 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020772
 protein coding gene Chr15:73962606-73966037 (+)
WSB/EiJ MGP_WSBEiJ_G0021242
 protein coding gene Chr15:74084841-74088277 (+)



Homology
more
  • Human Ortholog
    THEM6, thioesterase superfamily member 6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THEM6, thioesterase superfamily member 6
  • Synonyms
    C8orf55, DSCD75
  • Links
    NCBI Gene ID: 51337
    neXtProt AC: NX_Q8WUY1
    UniProt: Q8WUY1

  • Chr Location
    8q24.3; chr8:142727223-142736927 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Them6
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223626 NCBI Gene Model | MGI Sequence Detail 3140 C57BL/6J ±  kb
transcript NM_198607 RefSeq | MGI Sequence Detail 1600 Not Specified  
polypeptide Q80ZW2 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 46
    Diseases 1
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory