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Galp Gene Detail
Summary
  • Symbol
    Galp
  • Name
    galanin-like peptide
  • Feature Type
    protein coding gene
  • IDs
    MGI:2663979
    NCBI Gene: 232836
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:6200089-6219136 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 3.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    724 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2663979
 protein coding gene Chr7:6200089-6219136 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031596
 protein coding gene Chr7:3260920-3282384 (+)
A/J MGP_AJ_G0031570
 protein coding gene Chr7:3175436-3194369 (+)
AKR/J MGP_AKRJ_G0031499
 protein coding gene Chr7:3390183-3410331 (+)
BALB/cJ MGP_BALBcJ_G0031578
 protein coding gene Chr7:3270487-3288800 (+)
C3H/HeJ MGP_C3HHeJ_G0031299
 protein coding gene Chr7:3246663-3267390 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032040
 protein coding gene Chr7:3438497-3467162 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029155
 protein coding gene Chr7:2876913-2895320 (+)
CAST/EiJ MGP_CASTEiJ_G0030662
 protein coding gene Chr7:3141491-3161403 (+)
CBA/J MGP_CBAJ_G0031256
 protein coding gene Chr7:3555220-3575466 (+)
DBA/2J MGP_DBA2J_G0031415
 protein coding gene Chr7:3204932-3223354 (+)
FVB/NJ MGP_FVBNJ_G0031368
 protein coding gene Chr7:3201843-3220506 (+)
LP/J MGP_LPJ_G0031500
 protein coding gene Chr7:3368575-3387197 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031407
 protein coding gene Chr7:3566193-3585672 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032069
 protein coding gene Chr7:3193928-3213565 (+)
PWK/PhJ MGP_PWKPhJ_G0030390
 protein coding gene Chr7:3365846-3385872 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030216
 protein coding gene Chr7:2775901-2796575 (+)
WSB/EiJ MGP_WSBEiJ_G0030757
 protein coding gene Chr7:3340498-3362404 (+)



Homology
more
  • Human Ortholog
    GALP, galanin like peptide
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GALP, galanin like peptide
  • Synonyms
    GAL
  • Links
    NCBI Gene ID: 85569
    neXtProt AC: NX_Q9UBC7
    UniProt: Q9UBC7

  • Chr Location
    19q13.43; chr19:56176008-56185775 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit resistance to diet induced obesity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    885
  • Tissues
    31
  • cDNA Data
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232836 NCBI Gene Model | MGI Sequence Detail 19048 C57BL/6J ±  kb
    transcript NM_178028 RefSeq | MGI Sequence Detail 650 BALB/c  
    polypeptide Q810H5 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 1
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 13
    • Earliest
      J:83518 Jureus A, et al., Distribution and regulation of galanin-like peptide (GALP) in the hypothalamus of the mouse. Endocrinology. 2001 Dec;142(12):5140-4
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory