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Tmem198 Gene Detail
Summary
  • Symbol
    Tmem198
  • Name
    transmembrane protein 198
  • Synonyms
    A230078I05Rik, Tmem198-1, Tmem198a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443133
    NCBI Gene: 319998
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:75456176-75462349 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 39.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443133
 protein coding gene Chr1:75456115-75462349 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016191
 protein coding gene Chr1:76057343-76063513 (+)
A/J MGP_AJ_G0016174
 protein coding gene Chr1:73403618-73409791 (+)
AKR/J MGP_AKRJ_G0016131
 protein coding gene Chr1:75437542-75443713 (+)
BALB/cJ MGP_BALBcJ_G0016129
 protein coding gene Chr1:73466215-73472381 (+)
C3H/HeJ MGP_C3HHeJ_G0015960
 protein coding gene Chr1:75770448-75776616 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016582
 protein coding gene Chr1:79011502-79017705 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014303
 protein coding gene Chr1:68962693-68968955 (+)
CAST/EiJ MGP_CASTEiJ_G0015544
 protein coding gene Chr1:75115443-75121629 (+)
CBA/J MGP_CBAJ_G0015933
 protein coding gene Chr1:81589023-81595087 (+)
DBA/2J MGP_DBA2J_G0016034
 protein coding gene Chr1:72722954-72729124 (+)
FVB/NJ MGP_FVBNJ_G0016037
 protein coding gene Chr1:71929117-71935288 (+)
LP/J MGP_LPJ_G0016106
 protein coding gene Chr1:77184663-77190848 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016057
 protein coding gene Chr1:84923555-84929720 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016629
 protein coding gene Chr1:75507432-75513602 (+)
PWK/PhJ MGP_PWKPhJ_G0015331
 protein coding gene Chr1:72199511-72205735 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015109
 protein coding gene Chr1:74863193-74869354 (+)
WSB/EiJ MGP_WSBEiJ_G0015606
 protein coding gene Chr1:75317001-75323175 (+)



Homology
more
  • Human Ortholog
    TMEM198, transmembrane protein 198
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM198, transmembrane protein 198
  • Synonyms
    TMEM198A
  • Links
    NCBI Gene ID: 130612
    neXtProt AC: NX_Q66K66
    UniProt: Q66K66

  • Chr Location
    2q35; chr2:219543663-219550595 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Tmem198
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    19 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    2
  • cDNA Data
    16
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051703 Ensembl Gene Model | MGI Sequence Detail 6174 C57BL/6J ±  kb
transcript ENSMUST00000050899 Ensembl | MGI Sequence Detail 2456 Not Applicable  
polypeptide ENSMUSP00000057865 Ensembl | MGI Sequence Detail 360 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 23
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory