Oxa1l MGI Mouse Gene Detail - MGI:1916339

Symbol

Oxa1l
Name

oxidase assembly 1-like
Synonyms

1810020M02Rik

Feature Type

protein coding gene
IDs

MGI:1916339
NCBI Gene: 69089
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr14:54598298-54607130 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 27.76 cM, cytoband C1
Mapping Data

3 experiments

SNPs within 2kb

344 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916339	protein coding gene	Chr14:54598291-54607130 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0021306	protein coding gene	Chr14:48301253-48310165 (+)
A/J	MGP_AJ_G0021265	protein coding gene	Chr14:47369258-47379167 (+)
AKR/J	MGP_AKRJ_G0021241	protein coding gene	Chr14:49084046-49093171 (+)
BALB/cJ	MGP_BALBcJ_G0021269	protein coding gene	Chr14:47341188-47350577 (+)
C3H/HeJ	MGP_C3HHeJ_G0021049	protein coding gene	Chr14:48765031-48775017 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021708	protein coding gene	Chr14:50761425-50770257 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019252	protein coding gene	Chr14:45790669-45799066 (+)
CAST/EiJ	MGP_CASTEiJ_G0020568	protein coding gene	Chr14:45001556-45018721 (+)
CBA/J	MGP_CBAJ_G0021016	protein coding gene	Chr14:52255438-52266894 (+)
DBA/2J	MGP_DBA2J_G0021137	protein coding gene	Chr14:47115041-47124322 (+)
FVB/NJ	MGP_FVBNJ_G0021119	protein coding gene	Chr14:46569257-46578095 (+)
LP/J	MGP_LPJ_G0021211	protein coding gene	Chr14:49313527-49322514 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021143	protein coding gene	Chr14:51693691-51710164 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021734	protein coding gene	Chr14:48266078-48276352 (+)
PWK/PhJ	MGP_PWKPhJ_G0020314	protein coding gene	Chr14:43640552-43650031 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020142	protein coding gene	Chr14:44260030-44268722 (+)
WSB/EiJ	MGP_WSBEiJ_G0020621	protein coding gene	Chr14:48560716-48570571 (+)

Human Ortholog

OXA1L, OXA1L mitochondrial inner membrane protein

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

OXA1L, OXA1L mitochondrial inner membrane protein
Synonyms

OXA1, OXA1L1
Links

HGNC:8526

NCBI Gene ID: 5018

neXtProt AC: NX_Q15070

UniProt: Q15070
Chr Location

14q11.2; chr14:22766522-22773042 (+) GRCh38

MGI Vertebrate Homology

Oxa1l stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: OXA1L
Gene Tree

Oxa1l

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Phenotype Summary

6 phenotypes from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

3
Targeted

2
Genomic Mutations

1 involving Oxa1l
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

31 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

31
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

125
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase oxa1l

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All Sequences

59
RefSeq

2
UniProt

6
CCDS

CCDS27086.1

Ensembl

ENSMUSG00000000959 (Evidence)
NCBI Gene

69089

			Length	Strain/Species	Flank
genomic	69089	NCBI Gene Model \| MGI Sequence Detail	8833	C57BL/6J	± kb
transcript	NM_026936	RefSeq \| MGI Sequence Detail	2538	C57BL/6
polypeptide	Q8BGA9	UniProt \| EBI \| MGI Sequence Detail	433	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000012094 mitochondrial inner membrane protein OXA1L

(term hierarchy)
InterPro Domains

IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18

IPR028055 Membrane insertase YidC/Oxa/ALB, C-terminal

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All nucleic 126

cDNA 126

Microarray probesets 6

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MGI:2145708

Summaries

All 39

Developmental Gene Expression 1

Gene Ontology 7

Phenotypes 9
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Oxa1l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125623	Chr14:54598283-54598308 (+)	-2 bp
Tssr125624	Chr14:54598487-54598592 (+)	242 bp
Tssr125625	Chr14:54598749-54598806 (+)	480 bp
Tssr125626	Chr14:54600857-54600883 (+)	2,572 bp
Tssr125627	Chr14:54605320-54605343 (+)	7,034 bp
Tssr125628	Chr14:54605818-54605836 (+)	7,529 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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