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Mospd3 Gene Detail
Summary
  • Symbol
    Mospd3
  • Name
    motile sperm domain containing 3
  • Synonyms
    1190005J19Rik, 5133401H10Rik, Gtig2, R124
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916179
    NCBI Gene: 68929
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137594907-137599320 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 76.59 cM, cytoband Telomere
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    285 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916179
 protein coding gene Chr5:137594907-137599342 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030233
 protein coding gene Chr5:142369834-142374267 (-)
A/J MGP_AJ_G0030201
 protein coding gene Chr5:136160004-136165149 (-)
AKR/J MGP_AKRJ_G0030134
 protein coding gene Chr5:140591125-140595432 (-)
BALB/cJ MGP_BALBcJ_G0030211
 protein coding gene Chr5:137529996-137534200 (-)
C3H/HeJ MGP_C3HHeJ_G0029927
 protein coding gene Chr5:141239455-141243732 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030663
 protein coding gene Chr5:147625420-147630930 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027881
 protein coding gene Chr5:130405030-130408873 (-)
CAST/EiJ MGP_CASTEiJ_G0029337
 protein coding gene Chr5:140642934-140646842 (-)
CBA/J MGP_CBAJ_G0029897
 protein coding gene Chr5:153503115-153510116 (-)
DBA/2J MGP_DBA2J_G0030048
 protein coding gene Chr5:136062389-136066424 (-)
FVB/NJ MGP_FVBNJ_G0030003
 protein coding gene Chr5:135270786-135275155 (-)
LP/J MGP_LPJ_G0030137
 protein coding gene Chr5:142841892-142847161 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030035
 protein coding gene Chr5:156321629-156326897 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030704
 protein coding gene Chr5:140436376-140441502 (-)
PWK/PhJ MGP_PWKPhJ_G0029050
 protein coding gene Chr5:135152840-135157493 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028886
 protein coding gene Chr5:137999248-138003242 (-)
WSB/EiJ MGP_WSBEiJ_G0029410
 protein coding gene Chr5:141170525-141174695 (-)



Homology
more
  • Human Ortholog
    MOSPD3, motile sperm domain containing 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MOSPD3, motile sperm domain containing 3
  • Synonyms
    CDS3, NET30
  • Links
    NCBI Gene ID: 64598
    neXtProt AC: NX_O75425
    UniProt: O75425

  • Chr Location
    7q22.1; chr7:100612102-100615384 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice on some backgrounds display partial neonatal lethality with a thin right ventricular wall and dilated right ventricle. On other backgrounds no cardiac defects are detected.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    37
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037221 Ensembl Gene Model | MGI Sequence Detail 4414 C57BL/6J ±  kb
    transcript ENSMUST00000111007 Ensembl | MGI Sequence Detail 1318 Not Applicable  
    polypeptide ENSMUSP00000106636 Ensembl | MGI Sequence Detail 235 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      Genomic 1
      cDNA 38

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1274791, MGI:1925344
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:31729 Forrester LM, et al., An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1677-82
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory