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Aldh8a1 Gene Detail
Summary
  • Symbol
    Aldh8a1
  • Name
    aldehyde dehydrogenase 8 family, member A1
  • Synonyms
    RALDH4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2653900
    NCBI Gene: 237320
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:21253199-21272477 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 9.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    688 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2653900
 protein coding gene Chr10:21253190-21272484 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017061
 protein coding gene Chr10:19176823-19196053 (+)
A/J MGP_AJ_G0017039
 protein coding gene Chr10:18443127-18462492 (+)
AKR/J MGP_AKRJ_G0017003
 protein coding gene Chr10:18778480-18797770 (+)
BALB/cJ MGP_BALBcJ_G0016997
 protein coding gene Chr10:18509304-18528660 (+)
C3H/HeJ MGP_C3HHeJ_G0016822
 protein coding gene Chr10:19097691-19116964 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017459
 protein coding gene Chr10:19667187-19687536 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015164
 protein coding gene Chr10:17409407-17429002 (+)
CAST/EiJ MGP_CASTEiJ_G0016404
 protein coding gene Chr10:19017884-19037283 (+)
CBA/J MGP_CBAJ_G0016794
 protein coding gene Chr10:20578975-20598120 (+)
DBA/2J MGP_DBA2J_G0016902
 protein coding gene Chr10:18320608-18339881 (+)
FVB/NJ MGP_FVBNJ_G0016897
 protein coding gene Chr10:18063165-18082382 (+)
LP/J MGP_LPJ_G0016977
 protein coding gene Chr10:18972451-18991790 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016927
 protein coding gene Chr10:20767566-20787743 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017497
 protein coding gene Chr10:18761318-18780632 (+)
PWK/PhJ MGP_PWKPhJ_G0016189
 protein coding gene Chr10:18232340-18251706 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015972
 protein coding gene Chr10:18929225-18948163 (+)
WSB/EiJ MGP_WSBEiJ_G0016466
 protein coding gene Chr10:18856426-18875695 (+)



Homology
more
  • Human Ortholog
    ALDH8A1, aldehyde dehydrogenase 8 family member A1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALDH8A1, aldehyde dehydrogenase 8 family member A1
  • Synonyms
    ALDH12, DJ352A20.2
  • Links
    NCBI Gene ID: 64577
    neXtProt AC: NX_Q9H2A2
    UniProt: Q9H2A2

  • Chr Location
    6q23.3; chr6:134917393-134950115 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    751
  • Tissues
    14
  • cDNA Data
    31
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 237320 NCBI Gene Model | MGI Sequence Detail 19279 C57BL/6J ±  kb
transcript NM_178713 RefSeq | MGI Sequence Detail 2243 C57BL/6  
polypeptide Q8BH00 UniProt | EBI | MGI Sequence Detail 487 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 31
    Primer pair 2
    Other 2

    Microarray probesets 4
References
more
  • Summaries
    All 45
    Developmental Gene Expression 7
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:273031 Teletin M, et al., Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium. Development. 2019 Jan 4;146(1):dev170225
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory